What class of drug is Tienam?

Imipenem is in a class of medications called carbapenem antibiotics. It works by killing bacteria. Cilastatin is in a class of medications called dehydropeptidase inhibitors. It works by helping imipenem stay active in your body for a longer period of time.

How do you give Tienam?

Method of administration TIENAM is to be reconstituted and further diluted (see section 6.2, 6.3 and 6.6) prior to administration. Each dose of ≤500 mg/500 mg should be given by intravenous infusion over 20 to 30 minutes. Each dose >500 mg/500 mg should be infused over 40 to 60 minutes.

What is Tienam used for?

Tienam is an antibiotic used in complicated infections, generally in hospital. It has been used to treat infections of the lungs, the urinary tract (structures that carry urine), the abdomen, skin and the reproductive system. It can also be used in patients whose immune system is weakened when they have a fever.

Is imipenem given IV?

For Intravenous Injection Only PRIMAXIN I.V. (Imipenem and Cilastatin for Injection) is a sterile formulation of imipenem (a thienamycin antibiotic) and cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase l), with sodium bicarbonate added as a buffer.

What bacteria is imipenem resistant?

Proteus and Salmonella species had complete susceptibility to imipenem. However, 20.9% of Coagulase-negative Staphylococci and 18.2% of Pseudomonas aeruginosa were resistant to this antibiotic. Escherichia coli isolates from urine and tracheal tube secretion samples had the highest susceptibility to imipenem.

What are the side effects of imipenem?

Side Effects Swelling, redness, pain, or soreness at the injection site may occur. This medication may also rarely cause upset stomach, nausea, vomiting, or diarrhea. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

What is primaxin used for?

This medication is used to treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic. It works by stopping the growth of bacteria.

Does imipenem cover MRSA?

Imipenem appears to be an effective antistaphylococcal agent against both MRSA and MSSA infections.

What bacteria does primaxin cover?

Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species.

What is the brand name of imipenem?

Primaxin IM (Imipenem and Cilastatin): Uses, Dosage, Side Effects, Interactions, Warning.