What are the 2 sub units of hCG?
What are the 2 sub units of hCG?
HCG is composed of two subunits, HCGα and HCGβ. During early pregnancy, HCG stimulates progesterone production in the corpus luteum, and injection of HCG is widely used to induce ovulation in assisted reproduction treatment (ART).
What is a positive alpha hCG test?
A positive hCG means that a woman is likely pregnant. However, false-positive tests can occur if a woman is post-menopausal or taking hormone supplements. The blood level of hcG in a woman with an ectopic pregnancy usually rises at a slower rate than normal.
What subunit of hCG is used in pregnancy test?
The hCG b-core fragment is the predominant form of hCG in urine from seven weeks of pregnancy until term. In addition, the free b-subunit is also present in early pregnancy, becoming a minor component (<1%) of total hCG during the remainder of pregnancy.
What is alpha-subunit?
Pituitary glycoprotein hormones are composed of two different subunits, the alpha- and beta-subunits. The alpha-subunit is common to all FSH, LH, and TSH, while the beta-subunit is specific for each of these hormones. We studied the effects of a potent LHRH antagonist on alpha-subunit and LH secretion in normal men.
What is the chemical formula for toluene in water?
EPA, 2005), the EPA considers that there is inadequate information to assess the carcinogenic potential of toluene. The chemical formula for toluene is C H CH , and its molecular weight is 92.15 g/mol. fractive liquid, that is slightly soluble in water.
What are the effects of high levels of toluene?
Human studies have reported developmental effects, such as CNS dysfunction, attention deficits, and minor craniofacial and limb anomalies, in the children of pregnant women exposed to high levels of toluene or mixed solvents by inhalation.
Which is the primary target organ for toluene toxicity?
The central nervous system (CNS) is the primary target organ for toluene toxicity in both humans and animals for acute (short-term) and chronic (long-term) exposures.
How many milligrams of toluene should I take?
In addition, there are numerous supportive animal studies including those showing reproductive and developmental effects at doses higher than that identified as the point of departure. (2) The Reference Dose (RfD) for toluene is 0.08 milligrams per kilogram body weight per day (0.08 mg/kg/d) based on increased kidney weight in rats.