Is lactoperoxidase a protein?

Lactoperoxidase (LPO) (EC 1.11. 1.7) is a heme-containing chain glycoprotein found in milk and other exocrine secretions such as saliva, tears and airways. Apart from LPO, this family of proteins includes myeloperoxidase (MPO), eosinophil peroxidase (EPO), and thyroid peroxidase (TPO).

What is lactoperoxidase system?

The Lactoperoxidase system (LP-s) consists of the production of an antibacterial compound from the thiocyanate ion catalysed by Lactoperoxidase in the presence of hydrogen peroxide. This antibacterial system is naturally found in various body fluids including tears, saliva and gastric juice.

What is lactoperoxidase labeling used for?

The lactoperoxidase : glucose oxidase catalyzed iodination technique has been used successfully to label the surface proteins of mouse peritoneal macrophages.

What is LPO biology?

Lactoperoxidase is a member of the heme peroxidase family of enzymes. In humans, lactoperoxidase is encoded by the LPO gene. Lactoperoxidase catalyzes the oxidation of several inorganic and organic substrates by hydrogen peroxide.

How does the lactoperoxidase system ( lp-s ) work?

2. What is the Lactoperoxidase system and how does it work? The Lactoperoxidase system (LP-s) consists of the production of an antibacterial compound from the thiocyanate ion catalysed by Lactoperoxidase in the presence of hydrogen peroxide.

Are there any risks to the lactoperoxidase system?

12 Benefits and Potential Risks of the Lactoperoxidase System of Raw Milk Preservation. of the bacteriostatic effect and there is no evidence to show that the long-term use of the LP-s would lead to any such microbiological risks, e.g. development or accumulation of toxin-producing bacteria.

What can lactoperoxidase be used for in milk?

Barrett et al. (1999) theorized that lactoperoxidase may have a role in the keeping quality of pasteurized milk treated at 72 °C for 15 sec. LPS has also been used as a preservation process in infant formula, ice cream, cream, cheeses and liquid whole eggs ( Ekstrand, 1994 ). Alice Alegria-Schaffer,

How does lactoperoxidase affect the innate immune system?

Innate immune system. It has been shown that lactoperoxidase in the presence of thiocyanate can trigger the bactericidal and cytotoxic effects of hydrogen peroxide under specific conditions, such as when hydrogen peroxide is present in the reaction mixtures in excess of thiocyanate.