How common is Parkes Weber Syndrome?

Parkes Weber syndrome (PWS) is a congenital disorder of the vascular system. It is an extremely rare condition, and its exact prevalence is unknown. It is named after British dermatologist Frederick Parkes Weber, who first described the syndrome in 1907….

How common is Klippel-Trenaunay syndrome?

Klippel-Trenaunay syndrome is estimated to affect at least 1 in 100,000 people worldwide.

What causes Parkes Weber Syndrome?

What causes Parkes Weber syndrome? In many patients, PWS is caused by a mutation in a gene called RASA1. This mutation can run in families. A patient with PWS can pass this mutation on to his or her children.

What is Parkes Weber?

What is Parkes Weber syndrome (PWS)? PWS is an exceptionally rare congenital (present at birth) vascular anomaly that results in a child having a large number of abnormal blood vessels. It’s similar to the more common Klippel-Trenaunay syndrome (KTS) and is treated in much the same way.

What kind of disorder is Parkes Weber syndrome?

Parkes Weber syndrome is a disorder of the vascular system, which is the body’s complex network of blood vessels.

How is Parkes Weber syndrome related to cm-AVM?

CM-AVM and some cases of Parkes Weber syndrome have the same genetic cause. Parkes Weber syndrome is a rare condition; its exact prevalence is unknown. Some cases of Parkes Weber syndrome result from mutations in the RASA1 gene. When the condition is caused by RASA1 gene mutations, affected individuals usually have multiple capillary malformations.

What is the spectrum of Sturge Weber syndrome?

SWS can be thought of as a spectrum of disease in which individuals may have abnormalities affecting all three of these systems (i.e. brain, skin and eyes), or only two, or only one. Consequently, the specific symptoms and severity of the disorder can vary dramatically from one person to another.