Guidelines

What SSRI or SNRI is safest during pregnancy?

What SSRI or SNRI is safest during pregnancy?

SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth. Most studies show that SSRIs aren’t associated with birth defects.

Do SNRIs have less side effects than SSRIs?

This kind of dual reuptake inhibition is similar to the TCAs, but like the SSRI class, SNRIs are associated with less serious side effects. Some of these side effects include initial increases in anxiety, insomnia, and restlessness, and possible sexual dysfunction and headaches as well.

What has more side effects SSRI or SNRI?

SSRI and SNRI drugs are both used to treat depression, but they function differently. SNRI drugs may be more effective, but they tend to produce more side effects.

What happens if you get pregnant while on Effexor?

Use of the antidepressant venlafaxine (brand name Effexor®) during early pregnancy may be linked to several birth defects, including heart defects, defects of the brain and spine, cleft lip and cleft palate, hypospadias, and gastroschisis.

Which antidepressant is most stimulating?

Prozac (fluoxetine) and Wellbutrin (bupropion) are examples of “energizing” antidepressants; whereas Paxil (paroxetine) and Celexa (citalopram) tend to be more sedating.

Are SNRIs safer than SSRIs?

While both SNRIs and SSRIs are safe and effective, SSRIs are prescribed more often because they have greater efficacy in regulating mood and are typically better tolerated with fewer side effects. However, SNRI medications have some distinct advantages over selective serotonin reuptake inhibitors (SSRIs).

What is the best SNRI antidepressant?

The Food and Drug Administration (FDA) has approved these SNRIs to treat depression:

  • Desvenlafaxine (Pristiq)
  • Duloxetine (Cymbalta) — also approved to treat anxiety and certain types of chronic pain.
  • Levomilnacipran (Fetzima)
  • Venlafaxine (Effexor XR) — also approved to treat certain anxiety disorders and panic disorder.

Which SSRI has the least side effects?

Overall, citalopram appears to be the best-tolerated SSRI, followed by fluoxetine, sertraline, paroxetine, and fluvoxamine. The latter 2 drugs are associated with the most side effects and the highest discontinuation rates because of side effects in clinical trials.

Can anxiety hurt my unborn baby?

High levels of anxiety, during pregnancy, have adverse effect on mother and baby (3, 9, 10). Anxiety, in early pregnancy, results in loss of fetus and in the second and the third trimester leads to a decrease in birth weight and increased activity of the Hypothalamus – Hypophysis–Adrenal axis (3, 4).

Is it safe to take a SNRI during pregnancy?

SNRIs are potent inhibitors of the reuptake of serotonin and norepinephrine, while SSRIs act upon serotonin alone 14 . Confirmatory data on SSRI use during pregnancy and the risk of PPHN are now needed; limited data are available on the risk of PPHN associated with SNRIs 7.

Is it safe to take SSRI’s during pregnancy?

Although SSRIs are the most commonly prescribed class of antidepressants during pregnancy, an increase in the use of other antidepressants, such as serotonin norepinephrine reuptake inhibitors (SNRIs), has also been observed 13. SNRIs are potent inhibitors of the reuptake of serotonin and norepinephrine, while SSRIs act upon serotonin alone 14.

What’s the difference between a SSRI and a SNRI?

SNRI vs. SSRI. The selective serotonin reuptake inhibitor (SSRI) class is another group of antidepressants. SSRIs block only the reuptake of serotonin, while SNRIs block the reuptake of both serotonin and norepinephrine.

What are the side effects of taking SSRI’s?

Gastrointestinal upset (such as constipation, diarrhea, or nausea) Sexual dysfunction (such as reduced desire or erectile dysfunction). SSRIs and SNRIs may also cause: An increase in suicidal thoughts and behaviors, particularly in children and young adults under the age of 25 years.