What is trypomastigote form?

The trypomastigote is the infective flagellated form of the parasite found in the blood of the mammalian hosts (blood trypomastigote) and in the hindgut of vectors (metacyclic trypomastigote).

What is Trypanosoma cruzi trypomastigote?

Trypanosoma cruzi in thick blood smears stained with Giemsa. A typical trypomastigote has a large, subterminal or terminal kinetoplast, a centrally located nucleus, an undulating membrane, and a flagellum running along the undulating membrane, leaving the body at the anterior end.

Is trypomastigote a Trophozoite?

In the hemoflagellates the terms amastigote, promastigote, epimastigote, and trypomastigote designate trophozoite stages that differ in the absence or presence of a flagellum and in the position of the kinetoplast associated with the flagellum.

What is the medical definition of a trypomastigote?

Medical Definition of trypomastigote. : any flagellate of the family Trypanosomatidae that has the typical form of a mature blood trypanosome.

How long does it take for trypomastigotes to leave the midgut?

In the fly’s midgut, the parasites transform into procyclic trypomastigotes, multiply by binary fission , leave the midgut, and transform into epimastigotes . The epimastigotes reach the fly’s salivary glands and continue multiplication by binary fission . The cycle in the fly takes approximately 3 weeks.

How does a trypomastigote enter a host cell?

Trypomastigotes enter host cells by three distinct mechanisms (Fig. 16.4B and C ), two of them involving an early interaction with host cell lysosomes. 1.

Where are promastigote and epimastigote forms found?

Typically the promastigote and epimastigote forms are found in insect hosts, trypomastigote forms in the mammalian bloodstream and amastigotes in intracellular environments.