What is cytarabine syndrome?

Cytarabine syndrome is a rare clinical condition characterized by fever, malaise, myalgia, arthralgia, and/or rash that occurs after receipt of cytarabine. Our patient developed fever, malaise, and diffuse body pain shortly following cytarabine initiation despite receiving prophylactic dexamethasone.

Does cytarabine cause neurotoxicity?

Both cytarabine and its metabolites can cause neurotoxicity through a DNA synthesis-independent process since adult neurons are postmitotic [7].

What is cerebellar toxicity?

Cerebellar toxicity is a dose-dependent secondary effect of cytarabine; high doses of this drug are therefore linked to the greatest risk of developing this syndrome.

What are the side effects of cytarabine?

Cytarabine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• nausea.
• vomiting.
• diarrhea.
• stomach pain.
• loss of appetite.
• sores in the mouth and throat.
• hair loss.
• muscle or joint pain.

Is Cytarabine a strong chemo?

Cytarabine is a type of chemotherapy drug and is also known by its brand name, Ara C. It is a treatment for: acute leukaemias (cancers of the blood) some lymphomas (cancers of the lymph glands)

How long does Cytarabine stay in your system?

Nadir: White blood cells: 7-10 days, platelets: 12-15 days. Nausea and vomiting. Mouth sores (usually occur 7-10 days after therapy).

How often is cytarabine given?

Intermittent dosing: Cytarabine may be given as intermittent intravenous doses of 3-5 mg/kg daily, for five consecutive days. This course of treatment can be repeated after an interval of 2 to 9 days and repeated until the therapeutic response or toxicity is exhibited.

What is acute ataxia?

Acute cerebellar ataxia is sudden, uncoordinated muscle movement due to disease or injury to the cerebellum. This is the area in the brain that controls muscle movement. Ataxia means loss of muscle coordination, especially of the hands and legs.

What is a cerebellar lesion?

Cerebellar lesions are most often associated with the clinical findings of ataxia, which may affect the limbs, trunk, or even speech (producing a specific type of dysarthria known as scanning speech), dysequilibrium as manifested by a wide-based gait, and muscular hypotonia.

Is cytarabine a strong chemo?

What kind of chemo is Cytarabine?

Drug type: Cytarabine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “antimetabolite.” (For more detail, see “How cytarabine works” section below).

What is the ICD 10 cm code for cerebellar stroke syndrome?

ICD-10-CM Code G46.4 Cerebellar stroke syndrome. G46.4 is a billable ICD code used to specify a diagnosis of cerebellar stroke syndrome. A ‘billable code’ is detailed enough to be used to specify a medical diagnosis.

Which is the ICD 10 cm version of hereditary cerebellar ataxia?

This is the American ICD-10-CM version of G11.9 – other international versions of ICD-10 G11.9 may differ. Applicable To. Hereditary cerebellar ataxia NOS. Hereditary cerebellar degeneration. Hereditary cerebellar disease. Hereditary cerebellar syndrome.

When to use g46.4 for cerebellar stroke syndrome?

Cerebellar stroke syndrome Billable Code G46.4 is a valid billable ICD-10 diagnosis code for Cerebellar stroke syndrome. It is found in the 2021 version of the ICD-10 Clinical Modification (CM) and can be used in all HIPAA-covered transactions from Oct 01, 2020 – Sep 30, 2021. ↓ See below for any exclusions, inclusions or special notations

What is the ICD 10 cm diagnosis code for ataxia?

Ataxia, ataxy, ataxic R27.0 ICD-10-CM Diagnosis Code R27.0 ICD-10-CM Diagnosis Code G31.9 Paralysis, paralytic (complete) (incomplete) G83.9 ICD-10-CM Diagnosis Code G83.9 ICD-10-CM Codes Adjacent To G11.9 Reimbursement claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.