What do you need to know about glimepiride?

The reference site for Glimepiride. Glimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug. It is sometimes classified as either the first third-generation sulfonylurea, or as second-generation. Glimepiride is an oral diabetes medicine that helps control blood sugar levels.

How are glimepiride and creatinine clearances related?

Lower relative total clearance and renal clearance of both glimepiride metabolites correlated significantly with lower creatinine clearance values. Of the 16 patients 12 required between 1 and 4 mg glimepiride to stabilize their fasting blood glucose. Glimepiride was well-tolerated and there were no drug-related adverse events.

How often to take glimepiride for type 2 diabetes?

Glimepiride dosing information. Usual Adult Dose for Diabetes Type 2: Initial dose: 1 to 2 mg orally once a day Maintenance dose: Increase in 1 or 2 mg increments no more frequently than every 1 to 2 weeks based on glycemic response Maximum dose: 8 mg per day Comments: -Administer with breakfast or first main meal of the day.

What was the original trade name for glimepiride?

Glimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug. It is sometimes classified as either the first third-generation sulfonylurea, or as second-generation. WHAT IS GLIMIPIRIDE?

Can a person with Type 2 diabetes take glimepiride?

Glimepiride is used to help maintain blood sugar control in people with type 2 diabetes. It may cause nausea and people who take glimepiride should always be alert for symptoms of hypoglycemia (low blood sugar).

When to take glimepiride as an adjunct to diet?

-When patients are being transferred to this drug from a longer half-life sulfonylurea, monitor 1 to 2 weeks for overlapping drug effect. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Not recommended because of adverse effects on body weight and hypoglycemia.

How often should I increase my glimepiride dose?

Glimepiride dosing information Usual Adult Dose for Diabetes Type 2: Initial dose: 1 to 2 mg orally once a day Maintenance dose: Increase in 1 or 2 mg increments no more frequently than every 1 to 2 weeks based on glycemic response