Is glycogen phosphorylase the same as alpha 1 4 glucosidase?

Phosphorylase can only cleave α-1,4- glycosidic bond between adjacent glucose molecules in glycogen but branches also exist as α-1,6 linkages.

Does alpha-glucosidase break down glycogen?

Acid alpha-glucosidase normally breaks down a complex sugar called glycogen into a simpler sugar called glucose. Glucose is the main energy source for most cells.

Which molecule must be excluded from the active site of glycogen phosphorylase?

Subsites 5-2 are the primer subsites. First, in the reaction of phosphorylase a glucosyl residue is transferred to a phosphate group rather than to a water molecule. Consequently the exclusion of water from the active site is of essence for the phosphorylase reaction.

Is glycogen phosphorylase a transferase?

Glycogen phosphorylase, the key enzyme in glycogen breakdown, cleaves its substrate by the addition of orthophosphate (Pi) to yield glucose 1-phosphate. The cleavage of a bond by the addition of orthophosphate is referred to as phosphorolysis.

What is the function of acid alpha glucosidase?

Acid alpha-glucosidase is the enzyme responsible for degradation of glycogen polymers to glucose in the acidic milieu of the lysosomes.

Are there any other enzymes similar to alpha glucosidase?

Maltase, a similar enzyme that cleaves maltose, is nearly functionally equivalent. Other glucosidases include: Alpha-glucosidase hydrolyzes terminal non-reducing (1→4)-linked alpha-glucose residues to release a single alpha-glucose molecule.

Why is S.cerevisiae alpha glucosidase UED?

Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. Deficiency of alpha-1,4-glucosidase may cause GLYCOGEN STORAGE DISEASE TYPE II. Why S. cerevisiae alpha-glucosidase is ued for in-vitro and in-silico/docking enzyme inhibition studies?

How is hemozoin synthesis dependent on alpha glucosidase?

Hemozoin synthesis is dependent on the substrate binding site of alpha-glucosidase. Trout liver alpha-glucosidases were extracted and characterized. It was shown that for one of the trout liver alpha-glucosidases maximum activity of the enzyme was increased by 80% during exercise in comparison to a resting trout.