How is drug-induced thrombocytopenia treated?

Thus, the primary treatment for drug-induced thrombocytopenia is to discontinue the suspected causative agent. Patients experiencing life-threatening bleeding may benefit from intravenous immunoglobulin (IVIG) therapy, plasmapheresis, or platelet transfusions [9;10].

Is prednisone used to treat thrombocytopenia?

Corticosteroids have been used for more than 30 years as a first-line treatment for adult immune thrombocytopenia (ITP). The most common regimen is oral prednisone 1 mg/kg/d, slowly tapering to the lowest possible dose (based on platelet count) during a period of weeks.

Why is prednisone used for thrombocytopenia?

Prednisone is designed to increase the blood platelet count by slowing the destruction of platelets. Prednisone temporarily suppresses the body’s immune system so it stops destroying platelets.

How is pediatric ITP treated?

When treatment is needed, the two most common forms of treatment are steroids and immune globulin: Corticosteroids. Brief treatment with steroid medicine helps prevent bleeding by decreasing platelet destruction. Steroids can increase the platelet count in 2 to 3 weeks.

How is Prednisone used to treat idiopathic thrombocytopenic purpura?

Prednisone was used in the treatment of 30 consecutive patients with ITP (idiopathic thrombocytopenic purpura) under conditions that permitted the establishment of a satisfactory base line for metabolic and hematological studies, especially as to platelet count and other coagulation studies.

Which is the best treatment for drug induced thrombocytopenia?

Thus, the primary treatment for drug-induced thrombocytopenia is to discontinue the suspected causative agent. Patients experiencing life-threatening bleeding may benefit from intravenous immunoglobulin (IVIG) therapy, plasmapheresis, or platelet transfusions [9;10]. Corticosteroids seem inefficient in the treatment of DIT [11].

How is dit different from drug induced thrombocytopenia ( ITP )?

DIT can be distinguished from idiopathic thrombocytopenic purpura (ITP), a bleeding disorder caused by thrombocytopenia not associated with a systemic disease, based on the history of drug ingestion or injection and laboratory findings.

How are corticosteroids used to treat ITP in adults?

Corticosteroids have been used for more than 30 years as a first-line treatment for adult immune thrombocytopenia (ITP). 1 The most common regimen is oral prednisone 1 mg/kg/d, slowly tapering to the lowest possible dose (based on platelet count) during a period of weeks.