How do you get rid of keratosis Punctata?

Treatment includes keratolytics, topical salicylic acid, mechanical debridement, excision, and topical and systemic retinoids. Punctate keratosis of the palmar creases occurs most commonly in African American patients aged 15-40 years.

What causes keratosis Punctata?

In most families, punctate palmoplantar keratoderma type 1 is caused by a mutation in the AAGAB gene . The gene is thought to play an important role in skin integrity. When the gene is not working properly, the skin clumps together, forming the bumps on the skin that are characteristic of the condition.

What is keratosis punctata palmaris et plantaris?

Keratosis punctata palmaris et plantaris (KPPP) is a simple punctuate palmoplantar keratoderma that displays autosomal dominant inheritance with variable penetrance. Lesions typically begin between early adolescence and age 30 years as 2- to 20-mm hyperkeratotic papules along the lateral margins of the digits.

How do you treat keratosis punctata of the palmar creases?

Treatment options include topical keratolytics, emollients and occasionally systemic retinoids for severe cases. Systemic retinoids, such as etretinate, carry the risk of associated side effects such as hepatotoxicity.

What are palmar pits?

Palmar pits are small depressions in the skin on the palm of the hand that may be seen in individuals with basal cell nevus syndrome, a hereditary syndrome associated with the development of basal cell carcinoma. Depressions may also be seen on the sole of the foot (plantar pits, not shown).

How do you treat palmoplantar keratosis?

Treatment

1. Saltwater soaks.
2. Emollients.
3. Paring (cutting away layers of skin)
4. Topical keratolytics (useful for people with limited keratoderma)
5. Topical retinoids (this is often limited by skin irritation)
6. Systemic retinoids (acitretin)
7. Topical vitamin D ointment (calcipotriol)

What is Howel Evans syndrome?

Howel-Evans syndrome, also known as Clarke-Howel-Evans-McConnell syndrome, is a rare genetic disorder characterized by nonepidermolytic palmoplantar keratoderma (NEPPK), oral leukoplakia, and an increased risk of squamous cell carcinoma of the esophagus.

What is a keratosis of the skin?

An actinic keratosis (ak-TIN-ik ker-uh-TOE-sis) is a rough, scaly patch on the skin that develops from years of sun exposure. It’s often found on the face, lips, ears, forearms, scalp, neck or back of the hands.

How do you treat palmar pits?

Your doctor may prescribe a topical treatment that you put directly on your skin, including:

1. vitamin D analogs, such as calcipotriene (Dovonex)
2. topical corticosteroids.
3. topical retinoids.
4. anthralin.
5. coal tar products, which include creams, ointments, and gels that slow skin growth and ease itchiness.

Is palmoplantar psoriasis curable?

Palmoplantar psoriasis tends to be a long-term condition. There is no cure, but treatment can help control symptoms.

What is Olmsted syndrome?

Overview. Olmsted syndrome, also known as mutilating palmoplantar keratoderma (PPK) with periorificial keratotic plaques, is a very rare congenital (present from birth) disorder causing abnormal growth and thickening of skin.

What is Bloom syndrome?

Listen to pronunciation. (… SIN-drome) A rare, inherited disorder marked by shorter than average height, a narrow face, a red skin rash that occurs on sun-exposed areas of the body, and an increased risk of cancer.