Which group of drug is streptokinase?

Streptokinase can be useful in the management and treatment of acute ST-segment myocardial infarction, deep vein thrombosis, pulmonary embolism, arterial thrombosis or embolism, and arteriovenous cannula occlusion. It is in the thrombolytic class of medications.

What are the brand names of drugs?

Brand Name Drug Listing

What is streptokinase used to treat?

Streptokinase is used to dissolve blood clots that have formed in the blood vessels. It is used immediately after symptoms of a heart attack occur to improve patient survival. This medicine may also be used to treat blood clots in the lungs (pulmonary embolism) and in the legs (deep venous thrombosis) .

What is the side effect of streptokinase?

Acute allergic reactions to SK ranged from minor dyspnea, urticaria, pruritus, flushing, nausea, headache, or musculoskeletal pain to severe anaphylaxis, bronchospasm, or periorbital or angioneurotic edema. SK-induced fever has been reported in 30% to 50% of patients.

How does streptokinase work?

Streptokinase creates an active complex which promotes the cleavage of the Arg/Val bond in plasminogen to form the proteolytic enzyme plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.

What is a thrombolytic drug?

Thrombolytic therapy is the use of drugs to break up or dissolve blood clots, which are the main cause of both heart attacks and stroke.

What is brand name and generic name example?

For example, phenytoin is the generic name and Dilantin is a brand name for the same drug, which is a commonly used antiseizure drug.

What is the brand name of a drug mean?

A drug sold by a drug company under a specific name or trademark and that is protected by a patent. Brand name drugs may be available by prescription or over the counter.

How fast does streptokinase work?

1.9% in the group given aspirin alone. Streptase, Streptokinase, administered by the intracoronary route has resulted in thrombolysis usually within one hour, and ensuing reperfusion results in improvement of cardiac function and reduction of mortality (5,6) .

What is the most important complication of streptokinase therapy?

The most serious ADR was hemorrhagic stroke with a 1.4% incidence. Hypotension was one of the most occurred ADR (n = 75).

What is the antidote for streptokinase?

Drugs that can reverse effects of streptokinase include aminocaproic acid, aprotinin, and tranexamic acid.

Is streptokinase still used?

Currently, despite the wide use of tissue plasminogen activator in developed nations, streptokinase remains essential to the management of acute myocardial infarction in developing nations.