Which generation antihistamine is best?

Doctors consider them safe and effective treatments for minor allergies. Both are second-generation antihistamines. These cause less drowsiness than first-generation antihistamines. No research has concluded that Zyrtec or Claritin is more effective, but some people report better responses with one or the other.

What is the best first-generation antihistamine?

Diphenhydramine is a first-generation H1-antihistamine, a class of drugs that works by binding and stabilizing the H1-histamine receptor. It is found in a variety of allergy, cold, and sleep medications, with Benadryl as the best-known product.

Are 1st generation antihistamines more effective?

In conclusion, the use of first-generation H1-antihistamines should be discouraged in clinical practice today for two main reasons. First, they are less effective than second-generation H1-antihistamines.

What are older generation antihistamines?

The first-generation or “older” antihistamines (e.g., chlorpheniramine, diphenhydramine) are effective in reducing sneezing, itching, and rhinorrhea. They have untoward side effects, however, that are particularly notable in the elderly patient.

What is the best antihistamine?

Since histamine is the chief irritating chemical in allergies, an agent that works against it, such as antihistamine, proves highly effective. The most common antihistamine is benadryl, or diphendyramine.

What over-the-counter antihistamines are available?

Brompheniramine (brand names include Children’s Dimetapp Cold)

Do antihistamines dehydrate?

The simple answer is: Yes, OTC antihistamines often cause a dehydration of the sinus and mucus membranes. Perhaps they can even dehydrate any cell membrane in the body. I came to this conclusion after gathering the direct experiences from long-term antihistamine users, as well as my own.

Can antihistamines cause constipation?

Benadryl (diphenhydramine) may cause constipation, diarrhea, or abdominal pain in some patients. Benadryl and other antihistamines have anticholinergic effects which can cause dry mouth, dry eyes, thickening of bronchial secretions, urinary retention, blurred vision, drowsiness, and decreased gut motility (i.e. slower movement through the GI tract ).