What is Vermian hypoplasia?

Isolated inferior vermian hypoplasia (IIVH), also referred as part of Dandy-Walker variant (DWV), is a congenital malformation characterized by partial absence of the inferior portion of the cerebellar vermis.

How does cerebellar hypoplasia affect cats?

Cerebellar Hypoplasia, also known as CH and wobbly cat syndrome, is a neurological disorder that causes sudden jerky movements, uncoordinated motion and loss of balance. In a CH cat, the brain does not develop properly.

Is cerebellar hypoplasia in cats genetic?

Though cerebellar hypoplasia is most commonly regarded as a congenital hereditary disease in dogs, both pups and kittens can acquire this disease in utero if pregnant dogs and cats are infected by or vaccinated against specific infectious diseases (especially after panleukopenia infection or vaccination in cats).

What causes hypoplasia of the cerebellum?

It is believed that the cerebellar hypoplasia is due to a defect in the neuronal proliferation and neuronal migration during development of the embryonic nervous system. Cerebellar hypoplasia may result after an atrophy (destruction) of the cerebral cortex on the opposite side.

How rare is Dandy-Walker syndrome?

Dandy-Walker malformation is estimated to affect 1 in 10,000 to 30,000 newborns.

Can humans have cerebellar hypoplasia?

Cerebellar hypoplasia is a neurological condition in which the cerebellum is smaller than usual or not completely developed. Cerebellar hypoplasia is a feature of a number of congenital (present at birth) malformation syndromes, such as Walker-Warburg syndrome (a form of muscular dystrophy.

Can cerebellar hypoplasia be cured?

While there is no cure or treatment for this condition, as your puppy grows-up they can learn to compensate for their condition and go on to live a long, happy, and pain free life. Pets with cerebellar hypoplasia can often benefit from the use of a dog wheelchair to help support them and keep them mobile.

Is cerebellar hypoplasia painful?

Cerebellar hypoplasia is a developmental condition in which the cerebellum of the brain fails to develop properly. The cerebellum is the portion of the brain that controls fine motor skills, balance, and coordination. The condition is not painful or contagious.

Is there any cure for cerebellar hypoplasia?

While there is no cure or treatment for this condition, as your puppy grows-up they can learn to compensate for their condition and go on to live a long, happy, and pain free life.

How do you treat a cat with cerebellar hypoplasia?

There is currently no known treatment to cure your cat of cerebellar hypoplasia. Many cats will learn to adapt to their loss of fine motor skills over time. In some cases, physical therapy may help teach your cat alternate skills that may increase mobility and quality of life.

Do people get cerebellar hypoplasia?

VLDLR-associated cerebellar hypoplasia is an inherited condition that affects the development of the brain. People with this condition have an unusually small and underdeveloped cerebellum, which is the part of the brain that coordinates movement.

What is Walker syndrome?

Definition. Dandy-Walker Syndrome is a congenital brain malformation involving the cerebellum (an area of the back of the brain that coordinates movement) and the fluid-filled spaces around it.

Is there such a thing as isolated inferior vermian hypoplasia?

Dr Ayush Goel and Dr Bruno Di Muzio ◈ et al. Isolated inferior vermian hypoplasia (IIVH), also referred as part of Dandy-Walker variant (DWV), is a congenital malformation characterized by partial absence of the inferior portion of the cerebellar vermis.

How to diagnose cerebellar hypoplasia in kittens?

Cerebellar hypoplasia is seen in kittens after in utero infection with feline panleukopenia virus. The condition is nonprogressive, and affected cats may make suitable pets. Diagnosis can be obtained antemortem using MRI.

Is the cerebellum normal after hypoplasia?

Cerebellar hypoplasia is a type of congenital morphological cerebellar abnormality in which the cerebellum has reduced volume, but a normal shape, and is stable over time 1,4.

Are there disorders of the cerebellar vermis in dogs?

A selective hypoplasia of the cerebellar vermis is also seen in dogs, and when combined with hydrocephalus and cyst-like dilatation of the fourth ventricle, the condition has been termed the Dandy-Walker syndrome, which may have a familial basis.