What is systemic inflammatory response syndrome?

Listen to pronunciation. (sis-TEH-mik in-FLA-muh-TOR-ee reh-SPONTS SIN-drome) A serious condition in which there is inflammation throughout the whole body. It may be caused by a severe bacterial infection (sepsis), trauma, or pancreatitis.

What are symptoms of systemic inflammatory response syndrome?

Clinically, the Systemic Inflammatory Response Syndrome (SIRS) is identified by two or more symptoms including fever or hypothermia, tachycardia, tachypnoea and change in blood leucocyte count.

What is the treatment for SIRS?

TREATMENT. Patients with SIRS or sepsis require immediate stabilization and treatment. It is recommended that treatment be centered on fluid resuscitation, antimicrobial therapy, infectious source control, and overall supportive care (e.g., pain control, nutrition).

What are the symptoms of systemic inflammation?

Inflammation isn’t always obvious. Swelling and joint pain are clear signs of systemic inflammation, but other signs include gum disease, unexplained rashes, fatigue, head-aches, and muscle stiffness.

What is the systemic response to inflammation?

A systemic inflammatory response occurs when the entire body gives an inflammatory response to a threat. An inflammatory response is one of the body’s defense mechanism against harmful agents or damage. When a harmful agent enters the body or the body is damaged, blood is increased to the affected area.

What are symptoms of chronic inflammatory response syndrome?

Chronic Inflammatory Response Syndrome (CIRS) This is the body’s “out of control” inflammatory response to a toxin (i.e. mold, Lyme , etc.) it can’t get rid of that causes a cascade of inflammatory and hormonal changes that can cause fatigue, pain, gastrointestinal and neurologic symptoms, sleep disturbances, and other damaging effects to the body.

What causes an inflammatory response?

The inflammatory response (inflammation) occurs when tissues are injured by bacteria, trauma, toxins, heat, or any other cause. The damaged cells release chemicals including histamine , bradykinin , and prostaglandins . These chemicals cause blood vessels to leak fluid into the tissues, causing swelling.