What is PKU and Wolfram syndrome?

Wolfram syndrome , which is also known by the acronym DIDMOAD, is an inherited condition characterized by diabetes insipidus (DI), childhood-onset diabetes mellitus (DM), a gradual loss of vision caused by optic atrophy (OA), and deafness (D).

How common is Wolfram syndrome?

The estimated prevalence of Wolfram syndrome type 1 is 1 in 500,000 people worldwide. Approximately 200 cases have been described in the scientific literature.

How many people in the US have Wolfram syndrome?

Wolfram Syndrome Type 1 Medical experts estimate between 15,000 and 30,000 patients worldwide have this disease, including 1,000-2,000 in the United States.

What causes Wolff Parkinson White syndrome ( WPW )?

Wolff–Parkinson–White syndrome (WPW) is one of several disorders of the conduction system of the heart that are commonly referred to as pre-excitation syndromes. WPW is caused by the presence of an abnormal accessory electrical conduction pathway between the atria and the ventricles.

What makes a Wolfram slide a guitar slide?

Wolfram. Perfecting the interface between you and your guitar. The material, weight and surface of a slide all have an immense effect on tone and feel, but very few slides are actually made with this in mind. A Wolfram slide is engineered from the ground up using a range of stunning materials, to perform as a guitar slide.

What are the features of diencephalic syndrome ( FTT )?

• Any feature of  Diencephalic syndrome (FTT, vomiting and emaciation- Anterior hypothalamus)  Precocious puberty (Tuber cinereum)  Hormone deficinecy • Features suggesting mass effect on Chiasma • Epilepsy:  Gelastic seizure * Destructive lesion of hypothalamus never causes precocious puberty 13.

What are the symptoms of WPW syndrome recurrent tachycardia?

SymptomsSymptoms The usual complaint of patients with WPW syndrome and recurrent tachycardia is usually rapid palpitations associated with chest discomfort, shortness of breath, lightheadedness or syncope. The onset and offset are typically sudden.