What is P domain?

The P Domain Has a β-Structural Motif. An amino acid sequence alignment of the P domains (18) of representative members of the SPC family—mammalian SPC2–SPC7, furin, and kexin—is given in Fig. ​ Vertical arrows indicate those β-strand side chains that form the inner hydrophobic core of the P domain.

How do you find the domain of a protein?

One way to identify a domain is to find the part of a target protein that has sequence or structural similarities with a template through homology alignment. Another way is to predict the domain boundaries from a protein sequence.

What are the three protein domains?

Four concrete examples of widespread protein modules are the following domains: SH2, immunoglobulin, fibronectin type 3 and the kringle. Molecular evolution gives rise to families of related proteins with similar sequence and structure.

What is multi domain proteins?

In SCOP, domains are defined as independent evolutionary units that can either form a single-domain protein on their own or recombine with others to form part of a multidomain protein. In other words, each domain (or evolutionary unit) has to recur in proteins in different evolutionary contexts.

What is difference between domain and motif?

A motif is a short conserved sequence pattern associated with distinct functions of a protein or DNA. It is often associated with a distinct structural site performing a particular function. A domain is also a conserved sequence pattern, defined as an independent functional and structural unit.

What is the difference between subunit and domain?

The key difference between protein subunit and domain is that a protein subunit is a separate polypeptide chain of a protein that assembles with other polypeptide chains to form a protein complex while, a protein domain is a contiguous region of the polypeptide chain of a protein that frequently folds independently …

What is the difference between domain and motif?

What is a putative domain?

Description. A putative DNA-binding domain with a conserved structure is found in several different protein families. The core structure of the domain consists of a three-helical fold that is architecturally similar to that of the “winged-helix” fold, but is topologically distinct.

What is the difference between a motif and a domain?

What is a domain in genetics?

Listen to pronunciation. (doh-MAYN) A specific physical region or amino acid sequence in a protein which is associated with a particular function or corresponding segment of DNA.

Are domains motifs?

A motif is a short conserved sequence pattern associated with distinct functions of a protein or DNA. A domain is also a conserved sequence pattern, defined as an independent functional and structural unit. Domains are normally longer than motifs.

What are examples of motifs?

Examples of Motif in Narrative Writing

• A repeated reference or visual of shattered glass (something in life is about to break)
• Recurring dishonest characters (to cue up the discovery of an unfaithful spouse)
• A character who constantly misplaces things (as the loss of someone or something significant is on the horizon)

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