What is diabetes insipidus PPT?

2. Definition Diabetes insipidus is a disorder of the posterior lobe of the pituitary gland characterized by a deficiency of antidiuretic hormone (ADH), or vasopressin. Great thirst (polydipsia) and large volumes of dilute urine characterize the disorder.

What is diabetes insipidus in kids?

Diabetes insipidus is a rare disorder that occurs when the kidneys release a large amount of fluid through the urine. Children with diabetes insipidus can pass between 3 and 20 quarts of urine in one day. By comparison, a healthy child typically passes 1 to 2 quarts of fluid a day.

What is meant by diabetes insipidus?

Diabetes insipidus (die-uh-BEE-teze in-SIP-uh-dus) is an uncommon disorder that causes an imbalance of fluids in the body. This imbalance leads you to produce large amounts of urine. It also makes you very thirsty even if you have something to drink.

What is the pathophysiology of diabetes insipidus?

Diabetes insipidus is caused by abnormality in the functioning or levels of antidiuretic hormone (ADH), also known of as vasopressin. Manufactured in the hypothalamus and stored in the pituitary gland, ADH helps to regulate the amount of fluid in the body.

What are the symptoms of diabetes insipidus ( DI )?

Diabetes insipidus (DI) is an uncommon condition with either relative or absolute lack of anti-diuretic hormone (ADH) leading to inability to concentrate the urine and subsequent polyuria/polydypsia and potentially fluid and electrolyte imbalance.

How to treat central diabetes insipidus in children?

Treatment for the symptoms of central diabetes insipidus begins with establishing the cause. Symptomatic management may include: Modified antidiuretic hormone medications, such as desmopressin (DDAVP), taken as a pill, injection or nasal spray

What are the symptoms of nephrogenic diabetes insipidus?

Nephrogenic diabetes insipidus is the result of a defect in the kidneys, which may be caused by: Symptoms of diabetes insipidus in children and adolescents may include: Excessive thirst, often intense, with the need to drink large amounts of water

What kind of medication is used for diabetes insipidus?

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as indomethacin (may be used in nephrogenic DI, but only when no better options exist) See Treatment and Medication for more detail. Diabetes insipidus (DI) is defined as the passage of large volumes (>3 L/24 h) of dilute urine (< 300m Osm/kg). DI has 2 major forms: central and nephrogenic.