What is a pleomorphic sarcoma?

Overview. Undifferentiated pleomorphic sarcoma (UPS) is a rare type of cancer that begins mostly in the soft tissues of the body. Soft tissues connect, support and surround other body structures. UPS usually occurs in the arms or legs. Less often it can happen in the area behind the abdominal organs (retroperitoneum).

How rare is pleomorphic sarcoma?

As with all sarcomas of soft tissue and bone, MFH is rare, with just a few thousand cases diagnosed each year. MFH of soft tissue typically presents in a patient that is approximately 50 to 70 years of age though it can appear at any age.

How aggressive is pleomorphic sarcoma?

Sarcomas account for less than 1% of all cancers. Undifferentiated Pleomorphic Sarcoma, formerly called Malignant Fibrous Histiocytoma, is a rare subtype identified by a lack specific immunohistochemical markers for a specific lineage of differentiation. These soft tissue tumors are aggressive and rapidly enlarge.

Where do true sarcomas arise from?

Sarcomas are rare cancers or malignant tumours of the connective tissues and can arise in the soft tissues such as muscle, fat, blood vessels, fibrous tissue and nerves or in the hard tissue elements such as bone and cartilage.

What is high grade sarcoma?

High-Grade Endometrial Stromal Sarcoma (HG-ESS) is a type of endometrial stromal tumor, which is a malignant tumor of the uterus. High-Grade Endometrial Stromal Sarcoma is mostly present in adult women, and both pre- and post- menopausal women may be affected.

What are the symptoms and signs of soft tissue sarcoma?

abnormal vaginal bleeding

What does sarcoma mean?

Definition of sarcoma : a malignant tumor arising in tissue (such as connective tissue, bone, cartilage, or striated muscle) of mesodermal origin

Is sarcoma malignant?

A sarcoma is a malignant tumor and a rare type of cancer that occurs in adults, children and teens.