Is Poland anomaly genetic?

Most cases of Poland syndrome are sporadic, which means they are not inherited and occur in people with no history of the disorder in their families. Rarely, this condition is passed through generations in families.

What is Poland syndrome caused by?

What Causes Poland Syndrome? The cause of Poland syndrome is unknown. It may be from a blockage of blood flow to the chest, shoulder, arm, and hand muscles while a baby is developing in the womb.

Who discovered Poland anomaly?

In 1841, Sir Alfred Poland described this chest wall anomaly in the Guy’s Hospital Gazette while still a medical student, based on findings of one cadaver dissection.

Who is Poland syndrome named after?

Poland Syndrome was named for the investigator (Poland A) who initially described the condition in 1841. According to reports in the medical literature, Poland Syndrome appears to be three times as common in males as females.

Where does the name Poland anomaly come from?

Named after Sir Alfred Poland, Poland anomaly (PA) is described as an underdevelopment or absence of the chest muscle (pectoralis) on one side of the body and webbing of the fingers (cutaneous syndactyly) of the hand on the same side (ipsilateral hand).

What are the genetic causes of Poland syndrome?

Rare cases of Poland syndrome are thought to be caused by a genetic change that can be passed down in families, but no related genes have been identified. Most cases of Poland syndrome are sporadic, which means they are not inherited and occur in people with no history of the disorder in their families.

What kind of underdevelopment is Poland anomaly?

Poland anomaly is an underdevelopment or absence of the chest muscle on one side of the body and webbing of the fingers of the hand on the same side. What is Poland anomaly?

How is the Poland anomaly and Adams Oliver syndrome related?

They hypothesized that the Poland anomaly and the Adams-Oliver syndrome result from the interruption of early embryonic blood supply in the subclavian arteries, and that the gene predisposing to this interruption follows an autosomal dominant pattern of inheritance.