How to choose the best baclofen dosage for You?

-Determination of the optimal dose requires individual titration. The lowest dose with an optimal response should be used. -A positive response consists of a significant decrease in muscle tone and/or frequency and/or severity of spasms. -Many patients require gradual increases in dose over time to maintain optimal response during chronic therapy.

What are the ingredients in baclofen 10mg tablets?

What Baclofen tablets contain. • The active substance (the ingredient that makes the tablet work) is baclofen. Each tablet contains 10mg of the active ingredient • The other ingredients are lactose, pregelatinised maize starch, maize starch, magnesium stearate, water.

How is baclofen administered in the spinal fluid?

There are 3 ways baclofen can be administered [ 1 ]: 1 As a cream, where it is absorbed through the skin 2 As oral tablets 3 As injections directly into the spinal fluid (intrathecally), using an implanted pump

What are the side effects of baclofen injections?

In a long-term clinical trial of 28 people with Multiple Sclerosis (MS), baclofen spinal cord injections reduced spasms and improved quality of life and functional independence [R]. In two clinical trials lasting 5 – 6 years 28 MS patients, baclofen injections reduced spasms and pain [R, R].

Which is the correct formula for baclofen USP?

The structural formula is: Baclofen USP is a white to off-white, odorless or practically odorless crystalline powder. It is slightly soluble in water, very slightly soluble in methanol and insoluble in chloroform. Each tablet, for oral administration, contains 10 mg or 20 mg Baclofen.

What are the inactive ingredients in baclofen tablets?

Each tablet, for oral administration, contains 10 mg or 20 mg Baclofen. In addition, each tablet contains the following inactive ingredients: colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate, potato starch, povidone.