How do you convert metoprolol IV to PO?

-When switching between oral and intravenous dosage forms, equivalent beta-blocking effect is achieved when doses in a 2.5:1 (Oral:I.V.) ratio is used. For example, if the patient is receiving an oral dose of 25 mg twice daily (50 mg/day), this would translate to 5 mg I.V. every 6 hours; consider reducing initial I.V.

Can IV ondansetron be given orally?

Conclusions: Flavored intravenous ondansetron administered orally is a safe and an effective option and can be considered in the absence of the oral forms of the drug.

Can I take ondansetron with metoprolol?

Interactions between your drugs No interactions were found between Metoprolol Tartrate and ondansetron. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

When do you give metoprolol IV?

50 mg PO every 6 hours for 48 hours; the first dose should be given 15 minutes after the last IV dose. In patients who did not tolerate the full IV dose, give 25 mg PO every 6 hours for 48 hours.

How long does a Zofran shot last?

Zofran (ondansetron) lasts about eight hours. It begins to work quickly and reaches peak concentration in about two hours. To prevent nausea, the dose is usually repeated eight hours after the first one.

How quickly does IV metoprolol work?

When the drug was infused over a 10-minute period, in normal volunteers, maximum beta blockade was achieved at approximately 20 minutes. Equivalent maximal beta-blocking effect is achieved with oral and intravenous doses in the ratio of approximately 2.5:1.

How fast does IV metoprolol work?

After intravenous injection metoprolol is very rapidly distributed with a half-life of 5 to 15 min. Within the dose range of 10 to 20 mg, the plasma concentrations rise linearly in relation to the size of the dose. Metoprolol exhibits stereo-specific pharmacokinetics.

When to take ondansetron 24 mg before chemotherapy?

24 mg dose PO once given 30 minutes before administration of single-day highly emetogenic chemotherapy, including cisplatin 50 mg/m2 or more. Multiday, single dose administration of ondansetron 24 mg has not been studied.

How much Ondansetron is in Zofran ODT tablets?

ZOFRAN ODT Tablets are a freeze-dried, orally administered formulation of ondansetron which rapidly disintegrates on the tongue and does not require water to aid dissolution or swallowing. Each 5 mL of ZOFRAN Oral Solution contains 5 mg of ondansetron HCl dihydrate equivalent to 4 mg of ondansetron.

When to switch to oral metoprolol after IV bolus?

May switch to oral dosing (50 to 100mg po q6h) after IV bolus therapy. Supraventricular tachycardias (PAT, A-fib/flutter): 5 to 15 mg (usually 5 mg) over 2.5 min at 7.5min intervals-usually a high response rate.

How much Ondansetron is in 1 mL of aqueous solution?

Each 1 mL of aqueous solution in the 2-mL single-dose vial contains 2 mg of ondansetron as the hydrochloride dihydrate; 9.0 mg of sodium chloride, USP; and 0.5 mg of citric acid monohydrate, USP and 0.25 mg of sodium citrate dihydrate, USP as buffers in Water for Injection, USP.