Can you cure Zollinger-Ellison syndrome?

Surgical removal of gastrinomas is the only cure for Zollinger-Ellison syndrome. Some gastrinomas spread to other parts of the body, especially the liver and bones. Finding and removing all gastrinomas before they spread is often challenging because many of the tumors are small.

When should you suspect Zollinger-Ellison syndrome?

A medical professional may suspect Zollinger-Ellison syndrome if blood drawn after the infusion shows an elevated gastrin level. Once a diagnosis is made, localizing the tumor is important. Most Gastrinoma are small lesions and therefore, localizing the tumor may be difficult.

Can ZES be cured?

Gastrinomas tend to grow slowly and are not always malignant. The five-year survival rate depends on whether tumors are cancerous and if they’ve spread. If they have not spread to the liver, the 5-year survival rate may be 90%. If surgery removes the gastrinoma, 20%-25% of patients are completely cured.

What are the causes and symptoms of Zellweger syndrome?

Zellweger syndrome is caused by mutations in any one of at least 12 genes; mutations in the PEX1 gene are the most common cause. It is inherited in an autosomal recessive manner.

What are the characteristic features of Zellweger syndrome?

There will also be distinct facial characteristics such as: Having a flattened face. Having a broad nasal bridge. Having a high forehead. Having up slanting palpebral fissures which is the space between the margins of their eyelids. Having epicanthal folds which is the fold of their skin of the upper eyelid that that is over both or one of the inner angles of their eye. Eyebrow ridges that are underdeveloped.

Is there a cure for Zellweger syndrome?

Currently, no cure for Zellweger syndrome is known, nor is a course of treatment made standard. Infections should be guarded against to prevent such complications as pneumonia and respiratory distress. Other treatment is symptomatic and supportive.

How is Zellweger syndrome diagnosed?

The diagnosis of Zellweger syndrome can be done by measuring the metabolic compounds in the blood of the infant which may be increased if they have this disorder. They may also show decreased levels of plasmologen after the infant is born by doing blood tests.