Can temozolomide be given IV?

Temozolomide is available in both oral and intravenous (IV) form. The dose, whether oral or intravenous, is dependent on your body size, the regimen your provider is following, and whether or not it is being used in conjunction with other chemotherapies or radiation therapy.

How is TEMODAR given?

Administer TEMODAR by intravenous infusion only. Infusion over a shorter or longer period of time may result in suboptimal dosing. Flush the lines before and after each infusion. TEMODAR for injection may be administered in the same intravenous line with 0.9% Sodium Chloride injection only.

Is TEMODAR cumulative?

The safety of Temodar was evaluated in Study MK-7365-006 [see Clinical Studies (14.2)]. Myelosuppression (thrombocytopenia and neutropenia) was the dose-limiting adverse reaction. It usually occurred within the first few cycles of therapy and was not cumulative.

How effective is Temodal?

Adding temozolomide to short-course radiotherapy after surgery boosted overall survival by nearly 2 months, bringing 1-year survival rates up from 22.2% to 37.8% for elderly patients with glioblastoma.

How should I take Temodar?

Zofran or Anzemet) one hour before taking Temodar to combat anticipated side effect of nausea.

What conditions does Temodar treat?

Temodar ( temozolomide) is a cancer medicine that interferes with the growth and spread of cancer cells in the body in the body. Temodar is used together with radiation therapy to treat certain types of brain tumor in adults. Temodar is usually given after other cancer medicines have been tried without success.

How to take Temodar?

Temodar for Injection should be administered only by intravenous infusion. Flush the lines before and after each Temodar infusion. Temodar for Injection may be administered in the same intravenous line with 0.9% Sodium Chloride injection only.

What does Temodar do?

TEMODAR (temozolomide) is a prescription medicine used to treat adults with certain brain cancer tumors. TEMODAR blocks cell growth, especially cells that grow fast, such as cancer cells. TEMODAR may decrease the size of certain brain tumors in some patients. It is not known if TEMODAR is safe and effective in children.