Can pancreatic cancer cause congestive heart failure?

We describe two cases of women with pancreatic cancer who underwent treatment with gemcitabine plus nab-paclitaxel and developed acute exacerbation of congestive heart failure that persisted even with single-agent gemcitabine. Common adverse events of nab-paclitaxel plus gemcitabine compared to gemcitabine alone.

Does pancreatic cancer affect the heart?

PTTM is most commonly associated with gastric cancer and more rarely associated with pancreatic cancer. We report a case of progressive right heart failure associated with clinically diagnosed pancreatic cancer, suggesting PTTM.

What is the pathophysiology related to heart failure?

A comparison of healthy heart with contracted muscle (left) and a weakened heart with over-stretched muscle (right). The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle, through damage or overloading.

Does cancer cause heart failure?

Some cancer treatments can cause heart disease, weakening of the heart muscle (cardiomyopathy), or heart tumors. Another condition, cardiac amyloidosis, is sometimes linked to multiple myeloma.

What is the pathophysiology of the disease pancreatitis?

Pathophysiology of Pancreatitis Pancreatitis is an obstructive disease in which the backup of pancreatic secretions causes the activation and release of enzymes within the pancreatic acinar cells.

How is the diagnosis of pancreatic cancer made?

Pancreatic cancer is diagnosed using imaging and biopsy, following suspicion of the disease based on a set of symptoms. Initial testing may involve an abdominal ultrasound or a CT scan.

What kind of cancer is in the head of the pancreas?

Cancer is an abnormal growth of cells. Most cancers of the pancreas are adenocarcinomas that arise in the ducts responsible for producing digestive enzymes to break down food. They tend to occur in the head of the pancreas and may grow quickly. About 10% of pancreatic cancers are endocrine or islet cell cancers.

What causes the autodigestion of the pancreas?

Pancreatitis is basically the autodigestion of the pancreas by the pancreatic enzymes caused by obstruction of pancreatic ducts (e.g. edema, tumor, inflammation, and gallstones) and other causes. But before anything else, let’s review the different types of pancreatic enzymes and their main role in our system.