How can TB treatment affect patients emotionally and psychologically?

Additionally, TB treatment is long and mentally exhausting with numerous side effects. Several anti-TB medicines like cycloserine, which is used for drug resistant TB, cause mental health problems such as anxiety, or psychosis.

Can TB medicine cause depression?

There is another aspect of TB and mental health connection, which is drug-induced psychosis. Several anti-TB medications like cycloserine may precipitate more severe forms of mental disorders—including major depression, anxiety or psychosis.

Can isoniazid be used for depression?

Isoniazid was thereafter widely prescribed for depression: hepatotoxicity ending its use as an antidepressant in 1961. Isoniazid monotherapy led to the emergence of drug resistant tuberculosis, stimulating new drug development.

What are the psychosocial concerns of a patient with tuberculosis?

Patients suffering from pulmonary tuberculosis are reported to have psychiatric disorders like depression [212], anxiety, psychosis [83], and also many psychosocial problems [37, 213] like increased smoking [74], increased alcohol consumption [87], divorce, and isolation from the family [36].

How to diagnose depression in patients with tuberculosis?

1 To determine the prevalence of depression in people with TB at the time of anti-TB treatment initiation, 2 To assess factors associated with baseline depression, 3 To determine the incidence (risk) of depression in patients with TB at 2 and 6 months after starting anti-TB treatment,

How long does it take for depression to go away with TB?

Anti-TB treatment will progressively reduce depressive symptoms so that those with depression at baseline will have reduced severity of depression (Patient Health Questionnaire-9; PHQ-9 scores) or no depression after 2 and 6 months treatment for TB.

What kind of drugs are used to treat tuberculosis?

Effective drug treatments were first developed in the 1940s. The currently recommended treatment for cases of drug-susceptible tuberculosis is a six-month regimen of four first-line drugs: isoniazid, rifampicin, ethambutol, and pyrazinamide [ 1

What is the success rate for TB treatment?

Directly observed treatment short-course (DOTS) for TB is being implemented in all health facilities. 9 In 2011, the anti-TB treatment defaulter rate, death rate and treatment success rate were 2.5%, 2.0% and 82.3%, respectively, in SNNPR. 32