How is the pKa of an acid related to its strength?

Here is the definition of pKa and a look at how it relates to acid strength. pK a is the negative base-10 logarithm of the acid dissociation constant (K a) of a solution. The lower the pKa value, the stronger the acid. For example, the pKa of acetic acid is 4.8, while the pKa of lactic acid is 3.8.

How to calculate the pKa value of phenazine?

pKa Data Compiled by R. Williams page-1 pKa Values INDEX Inorganic 2 Phenazine 24 Phosphates 3 Pyridine 25 Carboxylic acids 4, 8 Pyrazine 26 Aliphatic 4, 8 Aromatic 7, 8 Quinoline 27 HCO3 10.33* HSe– 11.00* 77 H2CrO4 -0.98 30 H 2S 7.00* 77 HCrO4 6.50* 2, 30 HS– 12.92* 77 HOCN 3.92 34

How to relate pH and PKA with the Henderson equation?

Relating pH and pKa With the Henderson-Hasselbalch Equation If you know either pH or pKa, you can solve for the other value using an approximation called the Henderson-Hasselbalch equation: pH = pKa + log ([conjugate base]/ [weak acid]) pH = pka+log ([A – ]/ [HA])

When did Susan Taylor crystallized the PKA Cα subunit?

In 1991, Susan Taylor and colleagues crystallized the PKA Cα subunit, which revealed the bi-lobe structure of the protein kinase core for the very first time, providing a blueprint for all the other protein kinases in a genome (the kinome).

What is the relationship between pKa and buffer capacity?

pKa and Buffer Capacity In addition to using pKa to gauge the strength of an acid, it may be used to select buffers. This is possible because of the relationship between pKa and pH: pH = pKa+ log10([A-]/[AH]) Where the square brackets are used to indicate the concentrations of the acid and its conjugate base. The equation may be rewritten as:

What are the different types of PKA vaules?

Acetic acid conjugate acid -6 Diethyl ether conjugate acid -3.5 Ethanol conjugate acid -2 Methanesulfonic acid -2 Hydronium ion -1.74 Nitric acid -1.5 Trifluoroacetic acid 0.5 Bisulfate ion 2.0 Benzoic acid 4.2 Anilinium ion 4.6 Acetic acid 4.8 Pyridinium ion 5.2 Carbonic acid 6.4 Thiophenol 6.6 Hydrogen sulfide 7.0 Peracetic acid 8.2 Phthalimide

Where can I find pKa values in water?

A pKa Values in Water Compilation (by R. Williams) is available as a PDF file. A pKa Values Compilation (by Dave Evans and D. H. Ripin) is available as a PDF file.