What causes parotid pleomorphic adenoma?

The causes of pleomorphic adenomas are still unknown and the risk factors have not been fully ascertained yet. In addition to age, risk factors may be related to smoking habits, alcohol abuse, a diet rich in cholesterol and previous radiation therapy treatments in the face and neck regions.

Is pleomorphic adenoma curable?

There are many types of benign salivary gland tumors, with names such as adenomas, oncocytomas, Warthin tumors, and benign mixed tumors (also known as pleomorphic adenomas). Benign tumors are almost always cured by surgery.

Is pleomorphic adenoma benign?

Pleomorphic adenoma is the most common benign salivary gland neoplasm. In most studies, it represents 45-75% of all salivary gland tumors; the annual incidence is approximately two to three and a half cases per 100,000 population.

What is the optimal treatment of pleomorphic adenoma of the parotid?

The optimal treatment is superficial or total parotidectomy with facial nerve preservation, which results in local control rates of 95% or higher. Radiotherapy (RT) is useful to obtain local control in patients with positive margins, unresectable tumors, and multifocal recurrences after prior resection.

Is there a pleomorphic adenoma in the parotid gland?

Epidemiology. Pleomorphic adenomas account for 70-80% of benign salivary gland tumors and are especially common in the parotid gland (see below) 1,6 . Patients are typically middle aged 1, and prior head and neck irradiation is a risk factor for the development of these tumors.

Is the parotid gland a benign or malignant tumor?

A large duct passes out of parotid gland and carries saliva into the oral cavity. Like any structure in the body, the parotid gland is prone to the formation of abnormal growths which may either be benign or malignant. One of the most common of these tumors in the parotid gland is a pleomorphic adenoma. What is a pleomorphic parotid adenoma?

How old do you have to be to have a parotid tumor?

31-year-old male underwent a right parotidectomy at age 23 for a large benign pleomorphic adenoma of the right parotid gland. Seven years after surgery the patient was diagnosed with a recurrent tumor and an MRI was ordered. The radiologist reported that there were too many tumors to accurately count.

Which is the most common malignant histology of the parotid?

Pleomorphic Adenoma. Pleomorphic adenomas are the most common benign histology of the parotid, mucoepidermoid carcinoma are the most common malignant histology of the parotid, and adenoid cystic carcinomas are the most common malignant histology of the submandibular and minor salivary glands. From: Oral, Head and Neck Oncology