Do benzodiazepines cause cross tolerance?

It has been demonstrated in experiments on rats that only the drugs of benzodiazepine structure are responsible for complete cross tolerance as regards the myorelaxant effect under application with phenazepam.

How does tolerance to drugs and alcohol work?

Usually, tolerance develops because metabolism of the drug speeds up (often because the liver enzymes involved in metabolizing drugs become more active) and because the number of sites (cell receptors) that the drug attaches to or the strength of the bond (affinity) between the receptor and drug decreases (see …

How long does it take for benzo tolerance to go down?

Tolerance to the anticonvulsant and muscle-relaxing effects of benzodiazepines occurs within a few weeks in most patients.

Is there a cross tolerance between alcohol and benzodiazapine?

Benzodiazapine drugs are often prescribed to people who suffer alcoholism and depression but there are concerns about the cross tolerance to the effectiveness of benzodiazapine for alcoholic. This is because benzodiazapine medications and alcohol are both central nervous system depressants

What are the most common drugs that cause cross tolerance?

Here are the most common drug classes for cross-tolerance: Sedatives: Drugs like benzodiazepines, alcohol, barbiturates, and sleep aids all act on similar receptors in the brain. Opioids: All Mayo Clinic lead to cross-tolerance within the class. Stimulants: Many stimulants can lead to cross-tolerance.

Is there such a thing as cross tolerance?

Interestingly, alcohol appears to have a potential to produce cross-tolerance with some dissimilar drugs such as nicotine. Thus, alcohol use may contribute to cross-tolerance to many drugs. Thus, alcohol use may contribute to cross-tolerance to many drugs.

Can a person develop cross tolerance to a stimulant?

For example, if a person develops tolerance to stimulant drugs, it is highly unlikely that the person would develop cross-tolerance to narcotic drugs, benzodiazepines, or barbiturates. Moreover, even though some drugs produce very similar effects, such as Valium and heroin, these drugs operate on different neurotransmitters in the brain.