How do you administer ORBACTIV?

ORBACTIV is administered intravenously. ORBACTIV should only be diluted in D5W. Do NOT use normal saline for dilution as it is incompatible with ORBACTIV and may cause precipitation of the drug.

How long does ORBACTIV stay in your system?

In humans, oritavancin is slowly excreted unchanged in feces and urine with less than 1% and 5% of the dose recovered in feces and urine, respectively, after 2 weeks of collection. Oritavancin has a terminal half-life of approximately 245 hours and a clearance of 0.445 L/h based on population pharmacokinetic analyses.

What is ORBACTIV used for?

This medication is an antibiotic used to treat serious bacterial infections of the skin. It works by stopping the growth of bacteria.

How do you administer Dalvance?

DALVANCE is administered via intravenous infusion, using a total infusion time of 30 minutes to minimize the risk of infusion-related reactions. Rapid intravenous infusions of DALVANCE can cause reactions that resemble “Red-Man Syndrome,” including flushing of the upper body, urticaria, pruritus, and/or rash.

How many mg of Orbactiv should I take?

The recommended dosing for ORBACTIV is a single 1200 mg dose administered by intravenous infusion over 3 hours in patients 18 years and older. 2.2 Preparation of ORBACTIV for Intravenous Infusion. ORBACTIV is intended for intravenous infusion, only after reconstitution and dilution.

How often can I take Orbactiv for cellulitis?

For the treatment of acute bacterial skin and skin structure infections (ABSSSI) due to gram-positive organisms, including cellulitis/erysipelas, major cutaneous abscesses, and wound infections.. 1200 mg IV once.

What’s the difference between oritavancin and Orbactiv?

There are 2 oritavancin products (ie, Orbactiv, Kimyrsa) that have differences in dose strengths, duration of infusion, reconstitution and dilution instructions, and compatible diluents Abscess, limb and subcutaneous (3.8%)

How long does a 1200 mg oritavancin effect last?

Specifically, oritavancin artificially prolongs the activated partial thromboplastin time (aPTT) for up to 120 hours (5 days), the prothrombin time (PT) and international normalized ratio (INR) for up to 12 hours, and the activated clotting time (ACT) for up to 24 hours after administration of a single 1200 mg oritavancin dose.