Do chief cells secrete Zymogens?

Gastric chief cells are generally located deep in the mucosal layer of the stomach lining, in the fundus and body of the stomach. Chief cells release the zymogen (enzyme precursor) pepsinogen when stimulated by a variety of factors including cholinergic activity from the vagus nerve and acidic condition in the stomach.

What are chief cells called?

Cell types The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases pepsinogen and chymosin. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with hydrochloric acid produced by gastric parietal cells.

Why do chief cells secrete pepsinogen and not pepsin?

Specific cells within the gastric lining, known as chief cells, release pepsin in an inactive form, or zymogen form, called pepsinogen. By doing so, the stomach prevents the auto-digestion of protective proteins in the lining of the digestive tract. Parietal cells produce HCl by secreting hydrogen and chloride ions.

What are chief cells and zymogen cells secrete?

Chief cells are also known as a zymogenic cell or peptic cells. Pepsinogen is activated into the digestive enzyme pepsin when it comes in contact with acid produced by gastric parietal cells. Hence, Zymogen cells and chief cells secrete pepsinogen.

What are the zymogenic cells of the gastric gland secrete?

It secretes pepsinogen and chymosin. Pepsinogen is a zymogen. It is activated into the pepsin, a digestive enzyme after mixing with hydrochloric acid of gastric juice. Thus, the correct answer is option A.

What do the chief cells of the stomach secrete?

Chief cells secrete Gastric Lipase which functions to break down fats into smaller fatty acids that can be further digested in the intestine. What cell secretes Rennin, also called Chymosin, and what is the function of this enzyme? Chief Cells. They actually secrete zymogen forms of pepsin and chymosin/rennin which is activated by gastric acids.

What kind of protein does the chief cell secrete?

The chief cells secrete pepsinogen, a moderately sized zymogen protein with a molecular weight of 40,400. Pepsin, an enzyme with a molecular weight of 32,700, is formed in the acidic environment of the stomach when pepsinogen loses its activation peptides. These activation peptides range in length from three to six, or even more, amino acids.