Is Lokelma like Kayexalate?

The FDA approved oral sodium zirconium cyclosilicate (ZS-9), to be marketed as Lokelma, for the treatment of hyperkalemia. The drug seems to work better than sodium polystyrene sulfonate (Kayexalate), reducing serum potassium levels within an hour and restoring normal levels after about 2 hours in most patients.

What is the brand name for Kayexalate?

Sodium polystyrene sulfonate is available as brand name Kayexalate and as generic brands Kalexate, Kionex, and SPS, as well as non-branded generics. Sodium polystyrene sulfonate can be administered as an oral suspension or in an enema.

What is Kayexalate the antidote for?

This medication is used to treat a high level of potassium in your blood. Too much potassium in your blood can sometimes cause heart rhythm problems. Sodium polystyrene sulfonate works by helping your body get rid of extra potassium.

Is Kayexalate discontinued?

All of the above formulations have been discontinued. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Kayexalate. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy.

Are there any drug interactions with Kayexalate in humans?

No formal drug interaction studies have been conducted in humans. Kayexalate has the potential to bind other drugs. In in vitro binding studies, Kayexalate was shown to significantly bind the oral medications (n=6) that were tested.

How much potassium is in a gram of Kayexalate?

sodium polystyrene sulfonate. KAYEXALATE is a cation-exchange resin prepared in the sodium phase, with an in vivo exchange capacity of approximately 1 mmol (in vitro approximately 3.1 mmol) of potassium per gram. The sodium content is approximately 4.1 mmol (100 mg) per gram of the drug. KAYEXALATE can be administered either orally or as an enema.

What’s the best way to take Kayexalate orally?

To give this medicine orally: Mix the Kayexalate powder with water, or with honey or jam to make it taste better. Avoid inhaling the oral powder while you are preparing a dose. Do not mix the powder with any juice or other liquid that contains potassium, such as orange juice.

How many jars of Kayexalate are there in the US?

Ensure an adequate volume of cleansing solution (up to 2 liters) is utilized. Kayexalate is a cream to light brown, finely ground powder and is available in 453.6 g jars. Kayexalate is contraindicated in patients with the following conditions: