What are the symptoms of low thiamine?

Early symptoms of thiamin deficiency are vague. They include fatigue, irritability, poor memory, loss of appetite, sleep disturbances, abdominal discomfort, and weight loss. Eventually, a severe thiamin deficiency (beriberi) may develop, characterized by nerve, heart, and brain abnormalities.

What are the symptoms of infantile beriberi?

Infantile Beriberi:

• pale skin.
• hoarseness.
• diarrhoea.
• oedema.
• vomiting.
• weight loss.

How long does it take for thiamine deficiency symptoms to occur?

Usually thiamine deficiency develops within 12 weeks of a deficient intake.

What does thiamine deficiency do?

In severe cases, thiamine deficiency can cause Wernicke-Korsakoff syndrome, which involves two types of closely related brain damage ( 1 , 29 , 30 ). It’s symptoms often include delirium, memory loss, confusion and hallucinations.

Are there any cases of thiamine deficiency in children?

Laboratory tests showed severe thiamine deficiency (TPPE 31.2%). In patients 1 and 2, treatment led to complete resolution of symptoms. The third infant, a 5-month-old girl, was admitted on October 10, 2003, well before the outbreak was recognized, with vomiting, fever, and ophthalmoplegia. Her condition deteriorated to seizures, apnea, and coma.

How long does it take for thiamine deficiency to go away?

After thiamine deficiency was diagnosed, she received large doses of thiamine (50 mg/day) for 2 weeks. Like the other 5 infants without neurologic involvement, her clinical signs and symptoms disappeared completely within 2 to 3 weeks of treatment, and TPPE levels normalized within 1 to 7 days.

Can a thiamine deficiency cause shortness of breath?

It is important to note that shortness of breath can have many causes, so this symptom alone is not usually a sign of thiamine deficiency. Summary Heart failure caused by thiamine deficiency can cause breathlessness. This can occur when fluid accumulates in the lungs.

What happens to food intake after taking thiamine?

After 22 days, the rats displayed a 69–74% decrease in food intake ( 3 ). ). In both studies, food intake rapidly increased to baseline after re-supplementation of thiamine. Summary Thiamine plays an important role in the control of the “satiety center.” One common symptom of thiamine deficiency is a loss of appetite. 2. Fatigue