Why would immunoglobulins be low?

Low levels of immunoglobulins mean your immune system isn’t working as well as it should. This can be caused by: Medicines that weaken your immune system, such as steroids. Diabetes complications.

What is considered a low IgG level?

Usually the IgG level is less than 400 mg/dL; 70% of patients will have very low or absent IgA content. Documentation of impaired production of specific antibodies or poor response to vaccines is fundamental for this diagnosis.

What causes low IgG levels in adults?

Secondary IgG deficiency may be caused by: Aging. Malnutrition. Chemotherapy medicines and long-term corticosteroids.

What does a low immunoglobulin level mean?

ANSWER. Low levels of immunoglobulins mean your immune system isn’t working as well as it should. This can be caused by: Medicines that weaken your immune system, such as steroids. Diabetes complications. Kidney disease or kidney failure. A weakened immune system that you were born with or developed (as with HIV/AIDS)

What does a high immunoglobulin A blood level mean?

Elevated IgA levels can be indicative of a number of conditions such as Rheumatoid Arthritis, Lupus, Cirrhosis and Hepatitis. High IgA levels may mean that a person has a condition known as Monocolonal Gammopathy.

What are normal IgA and IgG levels?

When suspected, the diagnosis can be confirmed by laboratory measurement of IgA level in the blood. SIgAD is an IgA level < 7 mg/dL with normal IgG and IgM levels (reference range 70–400 mg/dL for adults; children somewhat less).

What are the causes of low IgG and IgM?

Low levels of the IgG antibody can also be caused by Waldenstrom’s macroglobulinemia, a rare blood cancer that is characterized by an overproduction of the IgM antibody and subsequent suppression of production of other types of antibodies, including IgG.