Is isoprenaline and isoproterenol same?

Isoprenaline, or isoproterenol (Brand name: Isoprenaline Macure), is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma. It is a non-selective β adrenoceptor agonist that is the isopropylamine analog of epinephrine (adrenaline).

Which of physical properties belongs to isoprenaline?

Isoproterenol is a synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating properties. Isoproterenol exerts its effect on the beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and cardiac output.

Is isoproterenol still used?

Isoprenaline inhalers sometimes provided more than the 20 micrograms needed for a maximum effect on the bronchi, resulting in adverse reactions. Oral isoprenaline was also used to treat some forms of heart block, but is now therapeutically obsolete.

Is isoprenaline an agonist or antagonist?

S-isoprenaline is a β1 receptor agonist, while its R-enantiomer acts as a competitive antagonist of S-isoprenaline with approximately equivalent affinity. S-methadone significantly attenuates the effects of its R-enantiomer on contraction and respiration.

Are there any side effects to taking isoproterenol?

Isoproterenol has been reported to cause insulin resistance leading to diabetic ketoacidosis. The adverse effects of isoprenaline are also related to the drug’s cardiovascular effects.

What are the side effects of taking isoprenaline?

Adverse effects of isoprenaline include nervousness, headache, dizziness, nausea, visual blurring, tachycardia, palpitations, angina, Adams-Stokes attacks, pulmonary edema, hypertension, hypotension, ventricular arrhythmias, tachyarrhythmias, difficulty breathing, sweating, mild tremors, weakness, flushing, and pallor.

How does isoprenaline work as an adrenoreceptor agonist?

Isoprenaline is a β 1 and β 2 adrenoreceptor agonist and has almost no activity against alpha adrenergic receptors. Its agonist effects at TAAR1 provide it with a pharmacodynamic effects that resemble those of the endogenous trace amines, like tyramine.

What are the different uses of isoproterenol?

Uses of Isoproterenol: It is used to treat certain types of abnormal heartbeats. It is used to treat heart failure (weak heart). It is used to treat shock.