What is OCT of optic nerve?

Optical coherence tomography (OCT) is a non-invasive imaging technique routinely used in ophthalmology to visualize and quantify the layers of the retina. It also provides information on optic nerve head topography, peripapillary retinal nerve fiber layer thickness, and macular volume which correlate with axonal loss.

What is normal retinal nerve fiber layer thickness?

Mean RNFL thickness (360° measurement) ranged from 40 to 105 µm in OHT eyes, from 46 to 106 µm in normal eyes, and from 4 to 85 µm in glaucomatous eyes.

What does the nerve fiber layer do?

The nerve fiber layer consists of the axons of the ganglion neurons coursing on the vitreal surface of the retina to the optic disk. These axons are unmyelinated until they penetrate the sclera at the optic disk. Their myelination by oligodendrocytes at this point accounts for the white color of the optic disk.

Is the Oct nerve fiber layer intervisable over time?

So repeatability of retinal nerve fiber layer and retinal thickness measurements over time must also be considered when monitoring for progression of an ocular disease state. So researchers have determined that spectral domain OCT has an intervisit tolerance limit of 95% for average peripapillary retinal nerve fiber layer.

What is the nerve fiber layer in the right eye?

Peripapillary retinal nerve fiber layer (RNFL) thickness of a right eye with glaucoma. (a) Fundus photograph showing the location of the OCT scan.

What is optic disc and retinal nerve fiber layer change?

Glaucoma is a progressive optic neuropathy typified by characteristic optic disc and retinal nerve fiber layer (RNFL) change that often precedes characteristic visual field loss. Although assessment of the optic disc is the cornerstone of glaucoma management, clinical examination of the optic disc is subjective and can be imprecise.

Which is the thickest fiber layer in the retina?

The retinal nerve fiber layer (RNFL) or nerve fiber layer, stratum opticum, is formed by the expansion of the fibers of the optic nerve; it is thickest near the optic disc, gradually diminishing toward the ora serrata.