What is thrombolytic therapy used for?

Thrombolytic therapy is the use of drugs to break up or dissolve blood clots, which are the main cause of both heart attacks and stroke.

What is a contraindication for thrombolytic therapy?

Absolute contraindications for thrombolysis include the following: Gastrointestinal (GI) bleeding within the past 6 months. Active or recent internal bleeding. History of hemorrhagic stroke.

What are the indications for thrombolytic therapy in a stroke?

Thrombolysis Guidelines

• Diagnosis of ischemic stroke causing measurable neurologic deficit.
• Neurologic signs not clearing spontaneously.
• Neurologic signs not minor and isolated.
• Symptoms not suggestive of subarachnoid hemorrhage.
• Onset of symptoms less than 3 hours hours before beginning treatment.

What are the indications for thrombolytic therapy in the?

In some cases, thrombolytic therapy may be indicated in patients with severe RV dysfunction without resultant hypotension to prevent further decompensation. [ 43] Thrombolytic agents, including tissue plasminogen activator (tPA), result in accelerated lysis of clots and can be administered systemically or via a catheter.

How are thrombolytics used in the treatment of heart attack?

Thrombolytics are used in a number of conditions related to thrombotic occlusions of blood vessels including heart attack, stroke, deep vein thrombosis, pulmonary embolism, and acute peripheral arterial occlusion.

When to start thrombolytic therapy for myocardial ischemia?

Indications for Thrombolytic Therapy (All Required) Symptoms of myocardial ischemia. ST elevation greater than 0.1 mV in at least two contiguous leads or new left bundle branch block on presenting ECG. Onset of symptoms within 12 hours.

Are there any side effects to taking thrombolytics?

Like other drug classes, thrombolytics have a few side effects that may be expressed in certain people. Some of them include: