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Which portion of the antibody binds with the antigenic determinant?

Which portion of the antibody binds with the antigenic determinant?

paratope
The paratope is the part of an antibody which recognizes an antigen, the antigen-binding site of an antibody. It is a small region (15–22 amino acids) of the antibody’s Fv region and contains parts of the antibody’s heavy and light chains.

What does the antigen bind to on the antibody?

With protein antigens, the antibody molecule contacts the antigen over a broad area of its surface that is complementary to the surface recognized on the antigen. Electrostatic interactions, hydrogen bonds, van der Waals forces, and hydrophobic interactions can all contribute to binding.

Where are antigenic determinants found?

antigenic determinant a site on the surface of an antigen molecule to which a single antibody molecule binds; generally an antigen has several or many different antigenic determinants and reacts with many different antibodies. Called also epitope.

What is antigenic determinants on immunoglobulins?

An epitope, also known as an antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibodies, B cells, and T cells. The latter can use epitopes to distinguish between different antigens, and only binds to their specific antigen.

Which is part of an antibody does an antigenic determinant bind?

Antigenic determinants bind… Antigenic determinants bind to which of the following portions of an antibody? The specific region on an antigen that an antibody recognizes and binds to is called the epitope, or antigenic determinant. An epitope is usually 5-8 amino acids long on the surface of the protein.

How are antigenic determinants recognized by T cells?

Antigenic determinants recognized by T cells are created by the primary sequence of amino acids in proteins. T cells do not recognize polysaccharide or nucleic acid antigens. This is why polysaccharides are generally T-independent antigens and proteins are generally T-dependent antigens.

How are antigens bound to the epitope of an antibody?

Therefore, most antigens have the potential to be bound by several distinct antibodies, each of which is specific to a particular epitope. The antigen binding receptor on an antibody is called a paratope, and is specific to the epitope of the antigen.

How is hapten used as an antigenic determinant?

Site on antigen that directly contacts the antigen-binding pocketof the antibody or TCR Synonymous with antigenic determinant Define hapten. Low-molecular-weight compound that can act as an epitope but is only immunogenic if coupled to larger carrier molecule

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