Is phenethylamine a psychedelic?

Phenethylamines are stimulant, entactogenic, and hallucinogenic substances that share similar chemical structures with amphetamine, catecholamines, synthetic cathinones, and other substances (Nelson, Bryant, & Aks, 2014).

Is dopamine A phenethylamine?

Dopamine is simply phenethylamine with a hydroxyl group attached to the 3 and 4 position of the benzene ring. Several notable recreational drugs, such as MDMA (ecstasy), methamphetamine, and cathinones, are also members of the class. All of the substituted amphetamines are phenethylamines, as well.

What kind of drugs are in the phenethylamine class?

Phenethylamine. The class of substituted phenethylamines includes all substituted amphetamines, and substituted methylenedioxyphenethylamines (MDxx), and contains many drugs which act as empathogens, stimulants, psychedelics, anorectics, bronchodilators, decongestants, and/or antidepressants, among others.

How is the phenyl ring of phenethylamine classified?

Substituted phenethylamine. Hence, any substituted phenethylamine can be classified according to the substitution of hydrogen (H) atoms on phenethylamine’s phenyl ring, sidechain, or amino group with a specific group of atoms .

How is phenethylamine metabolized in the body?

Phenethylamine is sold as a dietary supplement for purported mood and weight loss -related therapeutic benefits; however, in orally ingested phenethylamine, a significant amount is metabolized in the small intestine by monoamine oxidase B (MAO-B) and then aldehyde dehydrogenase (ALDH), which converts it to phenylacetic acid.

What are the side effects of taking phenethylamines?

Phenethylamines induce stimulant and hallucinogenic effects but can also cause hallucinations, confusion, depression, dizziness, nausea, vomiting, diarrhea, headaches, and body pains (Nelson et al., 2014 ). Intoxication includes serotonin syndrome and profound cerebral vasculopathy ( Ambrose, Bennett, Lee, & Josephson, 2010 ).