Is pro BNP the same as NT-proBNP?

BNP and NT‐proBNP have emerged as powerful biomarkers in various cardiovascular diseases. Both markers can be detected in serum plasma using commercially available assays. The diagnostic performance of BNP and NT‐proBNP is comparable and there is no meaningful difference between them.

What does NT-proBNP tell you?

The NT-proBNP blood test measures brain natriuretic peptide to detect heart failure. If your doctor orders a BNP test, you are probably showing symptoms of heart failure. The test measures a hormone called “brain natriuretic peptide.”

What does high NT-proBNP mean?

If your BNP or NT-proBNP levels were higher than normal, it probably means you have heart failure. Usually, the higher the level, the more serious your condition is. If your BNP or NT-proBNP results were normal, it probably means your symptoms are not being caused by heart failure.

What does NT-proBNP do to the body?

A BNP test or NT-proBNP test can be used, along with other cardiac biomarker tests, to detect heart stress and damage and/or along with lung function tests to distinguish between causes of shortness of breath. Chest X-rays and an ultrasound test called echocardiography may also be performed.

What is the difference between BNP and NT proBNP?

You may hear your healthcare team refer to BNP or NT-proBNP levels, depending on the equipment used by the laboratory. BNP and NT-proBNP are measured as a simple blood test to help diagnose and monitor heart failure. BNP and NT-proBNP test results provide different values. At Cleveland Clinic, doctors rely mostly on NT-proBNP testing

When does NT-ProB type natriuretic peptide ( BNP ) go up?

NT-proB-type Natriuretic Peptide (BNP) blood test. Both BNP and NT-proBNP are released in response to changes in pressure inside the heart. These changes can be related to heart failure and other cardiac problems. Levels goes up when heart failure develops or gets worse, and levels goes down when heart failure is stable.

What is the mechanism behind the marker NT-proBNP?

NT-ProBNP: the mechanism behind the marker Brain natriuretic peptide (BNP) was isolated originally from porcine brain extracts but was soon defined as a cardiac natriuretic hormone. Together with the highly homologous atrial natriuretic peptide, it forms a dual natriuretic peptide system of the heart.

How does NT proBNP get out of the body?

Known mechanisms of BNP clearance from plasma include binding to the natriuretic peptide clearance receptor type-C and proteolysis by peptidase NEP 24.11. NT-proBNP has a longer half-life and thus higher plasma concentration than BNP.