What is meant by a palindromic sequence?

A DNA locus whose 5′-to-3′ sequence is identical on each DNA strand. The sequence is the same when one strand is read left to right and the other strand is read right to left. Recognition sites of many restriction enzymes are palindromic.

What is called a palindrome sequence of DNA?

A palindromic sequence is a sequence made up of nucleic acids within double helix of DNA and/or RNA that is the same when read from 5′ to 3′ on one strand and 5′ to 3′ on the other, complementary, strand. It is also known as a palindrome or an inverted-reverse sequence.

What is palindrome sequence example?

For a nucleotide sequence to be considered as a palindrome, its complementary strand must read the same in the opposite direction [2]. For example, the sequence 5′-CGATCG-3′ is considered a palindrome since its reverse complement 3′-GCTAGC-5′ reads the same. Palindromes can be exact or approximate.

What is palindromic sequence Class 12?

Note: A palindromic sequence is a sequence in double-stranded DNA or RNA molecule in which reading in a 5′- 3′ on one strand matches the sequence reading in the same direction on the complementary strand. Specific palindromic sequences are recognized by the restriction enzymes (restriction endonucleases) and cut them.

Which is the correct description of a palindromic sequence?

Palindrome of DNA structure A: Palindrome, B: Loop, C: Stem A palindromic sequence is a nucleic acid sequence in a double-stranded DNA or RNA molecule wherein reading in a certain direction (e.g. 5′ to 3′) on one strand matches the sequence reading in the opposite direction (e.g. 5′ to 3′) on the complementary strand.

How is the palindromic sequence recognized in EcoR1?

The restriction enzyme EcoR1 recognizes the following palindromic sequence: 5′- G A A T T C -3′ 3′- C T T A A G -5′ The top strand reads 5′-GAATTC-3′, while the bottom strand reads 3′-CTTAAG-5′. If the DNA strand is flipped over, the sequences are exactly the same (5’GAATTC-3′ and 3′-CTTAAG-5′).

What is the medical dictionary definition of palindrome?

Molecular biology Inverted repeat A sequence of duplex DNA or RNA with dyad symmetry that reads the same in the 5’ to 3’ direction on complementary strands; DNA-binding proteins may recognise palindromes. Segen’s Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Why are palindromic sequences important for bacterial restriction?

Bacterial restriction enzymes serve as protection against foreign DNA by destroying it. These enzymes are specific for palindromic sequences of double stranded DNA. Palindromes give structural strength to transcribed RNA by hydrogen bonding in hair-pin loops. Long palindromic sequences contain genes coding for r-RNA.