Is there a difference between carboplatin and cisplatin?
Is there a difference between carboplatin and cisplatin?
Cisplatin and carboplatin have different toxicity profiles; cisplatin is associated with a higher rate of nausea, vomiting, nephrotoxicity, ototoxicity, while carboplatin has a higher risk of myelosupresssion and neurotoxicity6.
What chemo drugs are used for adenocarcinoma of the lung?
The chemotherapy treatment plan for lung cancer often consists of a combination of drugs. Among the drugs most commonly used are cisplatin (Platinol) or carboplatin (Paraplatin) plus docetaxel (Taxotere), gemcitabine (Gemzar), paclitaxel (Taxol and others), vinorelbine (Navelbine and others), or pemetrexed (Alimta).
Which is better for Stage III cancer carboplatin or cisplatin?
Carboplatin-based CRT is associated with similar long-term survival but lower rates of toxicity. These findings suggest carboplatin may be the most appropriate chemotherapeutic agent for elderly stage III patients. Carboplatin-based CRT is associated with similar long-term survival but lower rates of toxicity.
Which is better cisplatin or gemcitabine for NSCLC?
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer In advanced NSCLC, cisplatin/pemetrexed provides similar efficacy with better tolerability and more convenient administration than cisplatin/gemcitabine.
How is cisplatin used to treat non small cell lung cancer?
ABSTRACT: Chemotherapeutic intervention in advanced and metastatic non-small-cell lung cancer (NSCLC) has changed over the past 2 decades. The improvements offered by cisplatin (Platinol)-based regimens, though significant in terms of survival and quality of life, were modest at best.
What are the results of paclitaxel in combination with carboplatin?
The next generation of phase I/II studies evaluated the efficacy of paclitaxel in combination with carboplatin. Results with this regimen have shown substantial promise, and 1-year survival rates as high as 54% have been reported.