What is prasugrel tablets used to treat?

Prasugrel is used along with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a heart attack or severe chest pain and have been treated with angioplasty (procedure to open the blood vessels that supply blood to the heart).

Is prasugrel better than clopidogrel?

In clinical studies, prasugrel has consistently demonstrated greater and more rapid platelet inhibition than clopidogrel in healthy subjects, patients with stable coronary artery disease (CAD) and acute coronary syndromes, and those undergoing PCI.

Is prasugrel on the PBS?

The PBAC recommended the listing of prasugrel on the PBS on the basis of acceptable cost effectiveness compared with clopidogrel. The PBAC accepted that prasugrel is more effective but causes a higher incidence of adverse bleeding events than clopidogrel.

What are the side effects of prasugrel?

Common side effects of Prasugrel include:

• Bleeding.
• Anemia.
• Atrial fibrillation.
• Back pain.
• Slow heart rate.
• Dizziness.
• Shortness of breath.
• Headache.

Which is the best dose of prasugrel to take?

The recommended dosage of prasugrel is a single 60 mg loading dose (6 × 10 mg tablets) followed by a maintenance dose of 10 mg once daily. 2 Prasugrel may be taken with or without food. 2 Prasugrel should be taken with aspirin as its effect has only been studied in this combination. 2 An aspirin dose of 75–150 mg daily is recommended long-term. 15

How is prasugrel used to prevent heart attacks?

Prasugrel is used to prevent strokes, heart attacks, or other serious problems with your heart or blood vessels. It is given to patients before they have a heart procedure called percutaneous coronary intervention (PCI). A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot.

What are the black box warnings for prasugrel?

Black Box Warnings Potential for significant, sometimes fatal, bleeding. Prasugrel can cause significant, sometimes fatal, bleeding; Do not use in patients with active pathological bleeding or a history of transient ischemic attack or stroke

When to give prasugrel to a bleeding patient?

Caution is urged when giving prasugrel to patients who have an increased risk of bleeding. This includes patients taking concomitant drugs, such as oral anticoagulants, non-steroidal anti-inflammatory drugs and fibrinolytics.