What is isoxsuprine used for in horses?

Isoxsuprine hydrochloride has been suggested for use in horses for treatment of navicular syndrome and laminitis. The drug has been shown to be a beta-adrenoreceptor antagonist with beta-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation.

Is isoxsuprine safe for horses?

Isoxsuprine is a vasodilator and should not be used in mares immediately after foaling or horses that are actively bleeding. Overdose of isoxsuprine increases the risk and severity of the aforementioned side effects.

What is the classification of isoxsuprine?

Isoxsuprine is in a class of drugs called vasodilators. Isoxsuprine relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.

What is the trade name for isoxsuprine HCL?

BRAND NAME(S): Vasodilan.

Why is isoxsuprine used in pregnancy?

Isoxsuprine (Vasodilan) is a beta-adrenergic that directly affects the vascular smooth muscle and results in peripheral vascular dilation. Isoxsuprine relaxes the uterine smooth muscles and is used for treatment of pre-term labor and dysmenorrhea.

How do I give isoxsuprine?

Isoxsuprine must be administered regularly to be maximally effective. -May administer with milk, food or antacid to avoid stomach upset. -Tablets may be crushed and added to corn syrup or cherry syrup to make into slurry/suspension just before administration. NOTE: Parenteral dosage form is not available in the US.

What does OsPhos do for horses?

OsPhos is an FDA approved, injectable bisphosphonate solution labeled for the control of clinical signs associated with navicular syndrome (caudal heal pain) in horses four years and older. OsPhos inhibits bone resorption (disappearance) by inhibiting cells called osteoclasts.

When should I take isoxsuprine?

Isoxsuprine is used to relieve the symptoms of central and peripheral vascular diseases such as arteriosclerosis, Buerger’s disease, and Raynaud’s disease.

When should I stop taking isoxsuprine?

Stop taking isoxsuprine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives). Stop taking isoxsuprine and contact your doctor if you develop a rash. dizziness or weakness.

Is isoxsuprine safe for pregnancy?

Isoxsuprine is in the FDA pregnancy category C. This means that it is not known whether isoxsuprine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

When should I drink isoxsuprine?

How to use Isoxsuprine HCL. This medication is taken by mouth with or without food, usually 3 to 4 times daily or as directed by your doctor. Dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it.

How long does horse OSPHOS last?

The most common adverse reactions were discomfort, agitation, pawing, and other signs of colic. In the safety study, several horses treated with OSPHOS developed soft or firm injection site swellings, which resolved within 10 days.