What is hereditary spastic Paraplegias?

Hereditary spastic paraplegia is a general term for a group of rare inherited disorders that cause weakness and stiffness in the leg muscles. Symptoms gradually get worse over time. It’s also known as familial spastic paraparesis or Strümpell-Lorrain syndrome.

Is Hereditary spastic paraplegia a disability?

HSP refers to a group of inherited neurologic disorders that cause progressive weakness and spasticity, or stiffness, in the lower extremities, mostly the leg and hip muscles. The long-term prognosis for people diagnosed with HSP varies: Some become very disabled, while others experience only mild disability.

Is HSP a disability?

The prognosis for individuals with HSP varies Some individuals are very disabled and others have only mild disability. The majority of individuals with uncomplicated HSP have a normal life expectancy. The prognosis for individuals with HSP varies Some individuals are very disabled and others have only mild disability.

Is HSP a form of MS?

HSP shares several clinical features of the progressive phase in Multiple Sclerosis (MS) which is a chronic neurodegenerative disease characterized by multiple areas of central nervous system (CNS) inflammation, demyelination and axonal loss.

Is spastic paraplegia dominant or recessive?

Genetic types of hereditary spastic paraplegia (HSP). Autosomal dominant, autosomal recessive, X-linked, and maternally inherited (mitochondrial) forms of HSP have been identified. Autosomal dominant HSP is the most common type of HSP, found in 75%-80% of affected individuals.

Is HSP similar to MS?

What are the different types of hereditary spastic paraplegias?

The hereditary spastic paraplegias (HSP) are a large group of inherited neurologic disorders that share the primary symptom of difficulty walking due to muscle weakness and muscle tightness (spasticity) in the legs. There are more than 80 different genetic types of HSP.

How many people have spastic paraplegia type 11?

Over 100 cases of spastic paraplegia type 11 have been reported. Although this condition is thought to be rare, its exact prevalence is unknown. Mutations in the SPG11 gene cause spastic paraplegia type 11. The SPG11 gene provides instructions for making the protein spatacsin.

Who is the founder of Spastic Paraplegia Foundation?

Others are Spastic Paraplegia, Hereditary Charcot-Disease, Spastic Spinal Paralysis, Diplegia Spinalis Progressiva, French Settlement Disease, Troyer syndrome, and Silver syndrome. The disorder was first identified in the late 1800s by A. Strümpell, a neurologist in Heidelberg, Germany.

What kind of Doctor treats spastic paraplegia 11?

Care for SPG11 is usually managed by a team including a primary care physician , neurologist, genetics professional ( geneticist and/or genetic counselor ), physical therapist , social worker, and psychologist. Treatment is focused on alleviating symptoms and may include: