What is cabergoline tablets used for?

Cabergoline is used to treat hyperprolactinemia (high levels of prolactin, a natural substance that helps breast-feeding women produce milk but can cause symptoms such as infertility, sexual problems, and bone loss in women who are not breast-feeding or men).

How quickly does cabergoline work?

The effect is prompt (within 3 hours from administration) and persistent (up to 7-28 days in healthy volunteers and hyperprolactinaemic patients, and up to 14-21 days in puerperal women). The Prolactin-lowering effect is dose related both in terms of degree of effect and duration of action.

What are the benefits of cabergoline?

The benefit of taking cabergoline is that it can reduce the level of prolactin in your blood and reduce the symptoms you have been experi- encing. It works by increasing a chemical in the brain called dopamine, which reduces the amount of prolactin that is produced.

What is the best time to take cabergoline?

Swallow the tablet with a drink of water, at a mealtime. Taking cabergoline with a meal will help to reduce the risk of feeling sick (nausea). Try to take cabergoline at the same time(s) of day each day; if you are taking it weekly, take it on the same day of the week each week.

Can cabergoline cause twins?

Eighty-five percent of women taking these medications ovulate, and of those who ovulate, 70 to 80 percent get pregnant. (The range is due to all the other factors affecting pregnancy, from your age to the quality of your partner’s sperm.) Bromocriptine and cabergoline do not increase your risk of having twins or more.

Does cabergoline work immediately?

Absorption: Following single oral doses of 0.5 mg to 1.5 mg given to 12 healthy adult volunteers, mean peak plasma levels of 30 to 70 picograms (pg)/mL of Cabergoline were observed within 2 to 3 hours.

Can I get pregnant while on cabergoline?

Cabergoline is taken as one to two tablets twice each week. Of the women treated, approximately 85% will ovulate and can become pregnant if no other causes of infertility are present.

Does cabergoline stop breast milk?

Cabergoline prevents/suppresses physiological lactation by inhibiting prolactin secretion. In controlled clinical trials, cabergoline given as a single 1 mg administration during the first day post-partum, was effective in inhibiting milk secretion, as well as breast engorgement and pain in 70 – 90% of the women.

Can folic acid help to conceive twins?

There have been some small studies that suggest folic acid may increase the likelihood of conceiving multiples. But there aren’t any large-scale studies to confirm that this increases your chances for multiples. If you are trying to get pregnant, taking folic acid will help protect your baby’s brain development.

Does cabergoline delay periods?

Our results showed that cabergoline can be used as a safe administration in PCOS patients with mild hyperprolactinemia to improve the menstrual irregularity. Use of cabergoline plus metformin is effective in improving irregular menstrual cycles and may reduce the required duration and dose of metformin.

What do you need to know about cabergoline tablets?

Cabergoline Description. Cabergoline USP is a white powder soluble in ethyl alcohol, chloroform, and N, N-dimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water. Cabergoline Tablets, USP for oral administration, contains 0.5 mg of Cabergoline USP.

What is the structural formula for cabergoline USP?

The structural formula is as follows: Cabergoline USP is a white powder soluble in ethyl alcohol, chloroform, and N, N-dimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water.

Is the white powder in cabergoline soluble in water?

Cabergoline USP is a white powder soluble in ethyl alcohol, chloroform, and N, N-dimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water.

What is the mechanism of action of cabergoline?

Mechanism of Action: The secretion of prolactin by the anterior pituitary is mainly under hypothalmic inhibitory control, likely exerted through release of dopamine by tuberoinfundibular neurons. Cabergoline is a long-acting dopamine receptor agonist with a high affinity for D2 receptors.