What is the indication for adenosine?

Intravenous Adenocard (adenosine injection) is indicated for the following. Conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT), including that associated with accessory bypass tracts (Wolff-Parkinson-White Syndrome).

What is the drug adenosine used for?

Diagnostically, adenosine is one pharmaceutical agent used in a myocardial perfusion stress imaging study for its vasodilatory effects. Therapeutically, adenosine is used for its antiarrhythmic properties in supraventricular tachycardia (SVT) and can function as a diagnostic tool as well, depending on the type of SVT.

What is adenosine used for in an emergency?

In the ED, adenosine is used to terminate supraventricular tachycardias (SVTs). It is also used by cardiologists for pharmacologic stress testing.

What is the action of adenosine?

In terms of its electrical effects in the heart, adenosine decreases heart rate and reduces conduction velocity, especially at the AV node, which can produce atrioventricular block.

What type of drug is adenosine?

Because of the effects of adenosine on AV node-dependent SVTs, adenosine is considered a class V antiarrhythmic agent.

How safe is adenosine?

Adenosine is an effective, safe drug for the diagnosis and treatment of paroxysmal tachycardias in adult and pediatric patients. A starting dose of 0.05-0.10 mg/kg as a rapid bolus injection is recommended for infants and children. An electrophysiologic effect can be expected within 20 seconds after injection.

What do you give for SVT?

Calcium channel or beta blockers can help correct heart rhythm. If you have SVT only 1 or 2 times a year, you may take beta-blockers or calcium channel medicines by mouth (orally) as needed. If your SVT is more frequent, you may need to take medicine every day.

Why is adenosine important?

In the body, adenosine helps in cellular energy transfer by forming molecules like adenosine triphosphate (ATP) and adenosine diphosphate (ADP). Adenosine also plays a role in signalling various pathways and functions in the body by forming signally molecules like cyclic adenosine monophosphate (cAMP).

Has anyone died from adenosine?

Two patients in the prehospital setting died immediately after receiving adenosine for presumed supraventricular tachycardia.

How does adenosine affect blood pressure?

adenosine causes a dose-related increase in heart rate and in systolic blood pressure, while producing only a slight decrease in diastolic blood pressure.4 It was hypothesized that these effects were the result of activation by adenosine of a reflex autonomic mech-anism that is probably blunted during anesthesia. The

Does adenosine lower blood pressure?

It is known that adenosine decreases blood pressure (BP) level as well as blood pressure variability (BPV).

Will you have hypotension with adenosine?

Adenosine is a potent peripheral vasodilator and can induce significant hypotension. The risk of serious hypotension may be higher in patients with autonomic dysfunction, hypovolemia, stenotic valvular heart disease, pericarditis or pericardial effusions, or stenotic carotid artery disease with cerebrovascular insufficiency.

Does adenosine stop the heart?

Adenosine will stop the heart — sometimes when a pt goes into a funky rhythm, it’s used to slow the rate in order to determine the rhythm.