What is reservoir drug delivery system?

Reservoir-based systems include a subset of microfabricated drug delivery systems and provide unique advantages. Reservoirs, whether external to the body or implanted, provide a well-controlled environment for a drug formulation, allowing increased drug stability and prolonged delivery times.

What is reservoir system?

In this discussion, a reservoir system is a water–hydrocarbon system contained within the pores of a rock unit. A reservoir system has three main components: a reservoir, an aquifer, and a transition zone (interface) between the two. An aquifer is a porous and permeable rock 100% saturated with water.

What is matrix and reservoir system?

In the reservoir patch, the membrane limits the rate of drug delivery; in the matrix system, it is the formulation of the drug/polymer matrix. Reservoir patches give tighter control of delivery rates but can have an initial burst of drug release.

What is matrix drug delivery system?

In a matrix or monolithic delivery system the drug is either molecular dissolved or dispersed inside a matrix. Compared to a reservoir system, a matrix system is not enveloped within a rate limiting membrane. As such the release rate of the drug from the matrix system is normally not constant and decreases in time.

What are the characteristics of the reservoir or membrane devices?

What are the characteristics of the reservoir or membrane devices? Explanation: These devices are used when the drug permeation through the stratum corneum is rapid than the rate of drug diffusion from the device. It is suitable for drugs which have low therapeutic indices.

What is matrix system in pharmaceutical industry?

The Matrix technology uses hydrophobic adhesives and/or uses a rate controlled membrane to deliver API (active pharmaceutical ingredient) through the skin, in turn providing for a longer delivery time — up to seven days.

What is matrix in pharmacy?

matrix is defined as a well-mixed composite of one or more. drugs with gelling agent i.e. hydrophilic polymers.

What is the difference between sustained and controlled release?

sustained release dosage forms follow first order kinetics whereas controlled forms follow zero order kinetics. In sustained forms the dosage is sustained for prolonged period of time and drug release is not definite per unit time but in controlled forms, drug release is very definite per unit time.

What is the difference between extended release and sustained release?

Sustained release’s definition is more akin to a “controlled release” rather than “sustained”. Extended-release dosage consists of either sustained-release (SR) or controlled-release (CR) dosage. SR maintains drug release over a sustained period but not at a constant rate.

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