What does NADH ubiquinone oxidoreductase do?

NADH:ubiquinone oxidoreductase catalyzes the oxidation of NADH, the reduction of ubiquinone, and the transfer of 4H+/NADH across the coupling membrane.

What protein product does the ND3 gene produce?

MT-ND3 is located in human mitochondrial DNA from base pair 10,059 to 10,404. The MT-ND3 gene produces a 13 kDa protein composed of 115 amino acids.

How large is NADH-Q Oxidoreductase?

Structure. NADH-Q oxidoreductase consists of approximately 46 polypeptide chains (>900kd). The genes encoding this proton pump resides in both the mitochondria and the nucleus. This enzyme is L-shaped, with a horizontal arm lying the membrane and a vertical arm that projects into the matrix.

Which etc complex is NADH dehydrogenase?

Complex I—NADH dehydrogenase NADH dehydrogenase, also known as NADH oxidoreductase, is a protein complex with one portion embedded into the inner mitochondrial membrane and another portion located in the mitochondrial matrix.

Where is NADH-ubiquinone oxidoreductase located outside the cell membrane?

Cited for: IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY. Complete GO annotation on QuickGO Protein located outside the cell membrane (s). Secreted The extracellular space is the space outside of the cell membrane but part of a multicellular organism.

What do you need to know about ubiquinone oxidoreductase?

NADH:ubiquinone oxidoreductase A Home-page for Complex I has recently been set up by Drs. Akemi and Takao Yagi at Scripps, and contains a more extensive set of information and links. The NADH:ubiquinone oxidoreductase (Complex I), provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle.

Where does the oxidation of NADH take place?

The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis. The complex occurs in the mitochondria of eukaryotes and in the plasma membranes of purple photosynthetic bacteria, and the closely related respiratory bacteria.

Where can I find information on NADH complex I?

A Home-page for Complex I has recently been set up by Drs. Akemi and Takao Yagi at Scripps, and contains a more extensive set of information and links. The NADH:ubiquinone oxidoreductase (Complex I), provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle.