What does the MU stand for in Mu phage?

Mu Bacteriophage Mu
Species: Escherichia virus Mu. Bacteriophage Mu, also known as mu phage or mu bacteriophage, is a muvirus (the first of its kind to be identified) of the family Myoviridae which has been shown to cause genetic transposition.

Is MU a temperate phage?

Bacteriophage Mu is a temperate phage of Escherichia coli K-12 and several other enteric bacteria (for a comprehensive monograph and references prior to 1987 see Symonds et al., 1987; for reviews see Howe, 1987a; Harshey, 1988; Pato, 1989).

How can bacteriophage mu be used as a transposable element?

Bacteriophage Mu E. Bacteriophage Mu replicates as a transposable element. Mu A protein remains bound to the Mu genome once inserted into the host genome, forming an oligomeric transpososome which promotes the transfer of the viral ends to other location of the host DNA, creating replication forks at each end.

What is a transposable phage?

Transposable phages are widespread in the bacterial world. Transposable bacteriophages have long been known to necessarily and randomly integrate their DNA in their host genome, where they amplify by successive rounds of replicative transposition, profoundly reorganizing that genome.

What is MU DNA?

DNA Transposition, DNA Repair, Genome Organization Mu is a lysogenic phage, capable of inserting into the host chromosome like a transposon. In the lytic cycle, Mu replicates by transposing randomly across the host chromosome.

What does a temperate phage do?

A bacteriophage that displays lysogenic life cycle in contrast to virulent phage that does not have the ability to display lysogeny (especially following mutation). Many temperate phages are capable of integrating their genome into the genome of their host.

What is MU transposition?

Mu is a lysogenic phage, capable of inserting into the host chromosome like a transposon. In the lytic cycle, Mu replicates by transposing randomly across the host chromosome. The transposition of Mu during the lytic cycle is estimated to occur about 100 times, revealing a robust transposition mechanism.

What is interrupted mating technique?

A technique used to MAP bacterial genes by determining the sequence in which donor genes enter recipient Cells. A gene MAPping technique in which bacterial conjugation is disrupted after specified time intervals.

What is the host of bacteriophage?

In fact, the word “bacteriophage” literally means “bacteria eater,” because bacteriophages destroy their host cells. All bacteriophages are composed of a nucleic acid molecule that is surrounded by a protein structure. A bacteriophage attaches itself to a susceptible bacterium and infects the host cell.

Is Temperada a lambda phage?

The wild type of this virus has a temperate life cycle that allows it to either reside within the genome of its host through lysogeny or enter into a lytic phase, during which it kills and lyses the cell to produce offspring.

What is temperate phage with example?

The bacteriophage that can enter into a lysogenic relationship with its host is called temperate phage. Examples of temperate bacteriophages are lambda (ʎ), ɸ 80, P1, P2 and Mu etc. A well-studied temperate bacteriophage is the phage lambda (ʎ) which can integrate into the chromosome of E. coli.

What are transposons in biology?

Transposons are DNA segments that are mobile. They can replicate and insert copies at sites within the same or a different chromosome. In the first class, the transposons is amplified by first transcribing a segment of DNA into RNA, and then reverse-transcribed into DNA.

What is the life cycle of phage Mu 4?

Life Cycle of Phage Mu 4. The Targets of Transposase. Phage Mu is also known as ‘bacteriophage Mu’. Since it infects the members of enterobacteria, it is also called ‘enterobacteria phage Mu’. It belongs to the family Myoviridae of the order Caudovirales and Group II dsDNA viruses.

Which is family of viruses does phage Mu belong to?

Phage Mu is also known as ‘bacteriophage Mu’. Since it infects the members of enterobacteria, it is also called ‘enterobacteria phage Mu’. It belongs to the family Myoviridae of the order Caudovirales and Group II dsDNA viruses. It is a temperate and transposable phage which causes transposition of genes at the time of its multiplication cycle.

How big is the head of phage Mu?

While Mu was specifically involved in several distinct areas of research (Including E. coli, maize, and HIV ), the wider implications of transposition and insertion transformed the entire field of genetics. Phage Mu is nonenveloped, with a head and a tail. The head has an icosahedral structure of about 54 nm in width.

Who was the first to discover the bacteriophage Mu?

Bacteriophage Mu, also known as mu phage or mu bacteriophage, is a mulikevirus (the first of its kind to be identified) of the family Myoviridae which has been shown to cause genetic transposition. It is of particular importance as its discovery in Escherichia coli by Larry Taylor was among the first observations…